A highly optimized and sensitive bowtie shape-based SPR biosensor for different analyte detection.

IF 4.6 3区 材料科学 Q2 CHEMISTRY, MULTIDISCIPLINARY Nanoscale Advances Pub Date : 2024-12-17 eCollection Date: 2025-01-28 DOI:10.1039/d4na00812j
Md Abu Huraiya, Sankar Ganesh Ramaraj, Sk Md Shahadat Hossain, Kisalaya Chakrabarti, Hitoshi Tabata, S M Abdur Razzak
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Abstract

With advancements in photonic technologies, photonic crystal fibers (PCFs) have become crucial components in developing highly sensitive and efficient biosensors. This paper presents an optimized bowtie-shaped PCF biosensor that leverages surface plasmon resonance (SPR) phenomena for enhanced refractive index (RI) sensing. The proposed design uses an external sensing mechanism to effectively characterize performance across an RI range of 1.32 to 1.44. Fabrication is simplified by selecting a large pitch and gold layer height, while performance is enhanced by increasing pitch size, improving the gold layer, and optimizing air hole diameter. Simulations performed using the finite element method in COMSOL Multiphysics v5.4 demonstrate an impressive wavelength sensitivity (WS) of 143 000 nm per RIU and an amplitude sensitivity (AS) of 6242 per RIU. The sensor also exhibits a high resolution of 6.99 × 10-7 RIU and maintains excellent full width at half maximum (FWHM) characteristics, resulting in a very high figure of merit (FOM) of 2600, indicating superior performance. These promising results suggest that the optimized bowtie-shaped PCF biosensor can be effectively applied to detect a wide range of biological and chemical substances with high precision and sensitivity.

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一个高度优化和敏感的基于领结形状的SPR生物传感器,用于不同的分析物检测。
随着光子技术的发展,光子晶体光纤(PCFs)已成为开发高灵敏度、高效率生物传感器的重要组成部分。本文提出了一种优化的领结形PCF生物传感器,该传感器利用表面等离子体共振(SPR)现象增强折射率(RI)传感。提出的设计使用外部传感机制在1.32至1.44的RI范围内有效地表征性能。通过选择较大的节距和金层高度简化了制造过程,同时通过增大节距尺寸、改进金层和优化气孔直径来提高性能。在COMSOL Multiphysics v5.4中使用有限元方法进行的模拟显示,每RIU的波长灵敏度(WS)为143,000 nm,振幅灵敏度(AS)为6242 nm。该传感器还具有6.99 × 10-7 RIU的高分辨率,并保持优异的半最大全宽度(FWHM)特性,从而获得2600的非常高的品质因数(FOM),表明优越的性能。这些结果表明,优化后的领结型PCF生物传感器可以有效地应用于多种生物和化学物质的检测,具有较高的精度和灵敏度。
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来源期刊
Nanoscale Advances
Nanoscale Advances Multiple-
CiteScore
8.00
自引率
2.10%
发文量
461
审稿时长
9 weeks
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