Regiodivergent Desymmetrization of meso-4,5-Epoxycyclohex-1-ene

IF 3.6 2区 化学 Q1 CHEMISTRY, ORGANIC Journal of Organic Chemistry Pub Date : 2024-12-26 DOI:10.1021/acs.joc.4c02214
Yiwei Wang, Miho Wakiya, Ryosuke Matsubara, Masahiko Hayashi
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Abstract

Herein, we report a regiodivergent desymmetrization of meso-4,5-epoxycyclohex-1-ene, which results in the formation of two enantioenriched structural isomers with high enantioselectivity from a single compound using a single chiral catalyst.

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中-4,5-环氧环己烯的区域发散不对称反应
在此,我们报道了中-4,5-环氧环己烯的区域分散脱对称,这导致一个化合物在单一手性催化剂下形成两个对映体富集的高对映选择性结构异构体。
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来源期刊
Journal of Organic Chemistry
Journal of Organic Chemistry 化学-有机化学
CiteScore
6.20
自引率
11.10%
发文量
1467
审稿时长
2 months
期刊介绍: Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.
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