Qun Liu, Xiaoyun Feng, Fenghao Xie, Yingchao Lai, Haokun Jiang, Yujing Jiao, Jin Wang
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Abstract
We herein report a photoredox N–S coupling reaction between dialkyl azodicarboxylates and thiols to access sulfenamide scaffolds. This reaction proceeds under mild, green, and operationally simple conditions, offering a broad scope of sulfenamides with high yields and excellent atom efficiency. Mechanistic investigations revealed this reaction followed a photoinitiated radical pathway in which iodide plays a crucial role as both a radical initiator and a single-electron reductant.
期刊介绍：
Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.
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