Serum Ethanol Concentrations in Relation to Sex and Age in Patients Admitted to a Large Emergency Department During 2015-2020.

IF 2.7 4区 医学 Q2 PHARMACOLOGY & PHARMACY Basic & Clinical Pharmacology & Toxicology Pub Date : 2025-01-01 DOI:10.1111/bcpt.14118
Aase Bratberg, Ilah Nygaard, Kari Løhne, Ingebjørg Gustavsen, Mimi Stokke Opdal
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Abstract

We examined the number of patients tested for serum ethanol concentration (SEC) at admission to a large Emergency Department (ED) and the relationship of SEC with sex and age. SEC was analysed by enzymatic method. We retrieved SEC in patient samples from the ED during 2015-2020 from the laboratory information system. Altogether, 174 378 patients were admitted, and 7.3% were tested for SEC. Of these, 35.3% had a positive test. The percentage of patients tested increased from 4.8% in 2015 to 14.4% in 2020. A total of 416 patients had more than one positive SEC. For individual data, we included the first positive test per patient, n = 3607. Of these, 73% were men and 27% were women. The median SEC for both men and women was 1.9 g/L. About 4.4% had a SEC ≥ 3.5 g/L. The median SEC in patients aged 30-59 years was 0.2 g/L higher than the 12-29 and ≥ 60 age groups. In conclusion, the increase in the percentage of patients tested did not lead to a corresponding increase in ethanol-positive tests. There was a large predominance of men, the median SEC was the same for men and women and highest in the 30-59 age group.

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2015-2020年大型急诊科住院患者血清乙醇浓度与性别和年龄的关系
我们研究了在一家大型急诊科(ED)入院时检测血清乙醇浓度(SEC)的患者数量,以及SEC与性别和年龄的关系。用酶法对SEC进行分析。我们从实验室信息系统中检索2015-2020年间急诊科患者样本中的SEC。总共有174 378名患者入院,7.3%的患者接受了SEC检测,其中35.3%的患者检测呈阳性。接受检测的患者比例从2015年的4.8%增加到2020年的14.4%。共有416例患者有一个以上的SEC阳性。对于个体数据,我们纳入了每个患者的第一个阳性检测,n = 3607。其中73%是男性,27%是女性。男性和女性的中位数SEC均为1.9 g/L。约4.4%的人SEC≥3.5 g/L。30-59岁患者的中位SEC比12-29岁和≥60岁年龄组高0.2 g/L。总之,接受检测的患者百分比的增加并没有导致乙醇阳性检测的相应增加。男性占多数,男性和女性的中位数SEC相同,在30-59岁年龄组中最高。
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来源期刊
CiteScore
5.60
自引率
6.50%
发文量
126
审稿时长
1 months
期刊介绍: Basic & Clinical Pharmacology and Toxicology is an independent journal, publishing original scientific research in all fields of toxicology, basic and clinical pharmacology. This includes experimental animal pharmacology and toxicology and molecular (-genetic), biochemical and cellular pharmacology and toxicology. It also includes all aspects of clinical pharmacology: pharmacokinetics, pharmacodynamics, therapeutic drug monitoring, drug/drug interactions, pharmacogenetics/-genomics, pharmacoepidemiology, pharmacovigilance, pharmacoeconomics, randomized controlled clinical trials and rational pharmacotherapy. For all compounds used in the studies, the chemical constitution and composition should be known, also for natural compounds.
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