Standard: Human gastric cancer organoids.

IF 4 Q2 CELL & TISSUE ENGINEERING Cell Regeneration Pub Date : 2024-12-27 DOI:10.1186/s13619-024-00217-7

Ronghui Tan, Fan Hong, Ting Wang, Nanshan Zhong, Hongling Zhao, Rui-Hua Xu, Lin Shen, Yingbin Liu, Xuebiao Yao, Dongxi Xiang, Dong Gao, Jianping Xiong, Lijian Hui, Bing Zhao, Zhifeng Miao, Jie Hao, Yong Li, Shijun Hu, Boqiang Fu, Guoqiang Hua, Lei Wang, Zhao-Lei Zeng, Chong Chen, Jianmin Wu, Changlin Wang, Chunnian Wang, Xianbao Zhan, Chen Song, Zhijian Sun, Chunping Yu, Yingying Yang, Gengming Niu, Yalong Wang, Tongbiao Zhao, Ye-Guang Chen

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Abstract

Gastric cancer is one of the most common malignancies with poor prognosis. The use of organoids to simulate gastric cancer has rapidly developed over the past several years. Patient-derived gastric cancer organoids serve as in vitro models that closely mimics donor characteristics, offering new opportunities for both basic and applied research. The "Human Gastric Cancer Organoid" is part of a series of guidelines for human gastric cancer organoids in China, jointly drafted by experts from the Chinese Society for Cell Biology and its branches, and initially released on October 29, 2024. This standard outlines terminology, technical requirements, assessment protocols, and applies to production, evaluation procedures, and quality control for human gastric cancer organoids. The publication of this guideline aims to assist institutions in endorsing, establishing, and applying best practices, advancing the international standardization of human gastric cancer organoids for clinical development and therapeutic application.

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标准：人胃癌类器官。

胃癌是最常见的恶性肿瘤之一，预后较差。在过去的几年里，使用类器官来模拟胃癌得到了迅速的发展。患者来源的胃癌类器官作为体外模型，密切模仿供体特征，为基础研究和应用研究提供了新的机会。《人胃癌类器官指南》是中国人胃癌类器官指南系列的一部分，由中国细胞生物学学会及其分支机构的专家共同起草，并于2024年10月29日首次发布。本标准概述了术语、技术要求、评估方案，并适用于人胃癌类器官的生产、评估程序和质量控制。本指南的发布旨在协助各机构认可、建立和应用最佳实践，促进人类胃癌类器官临床开发和治疗应用的国际标准化。

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来源期刊

Cell Regeneration Biochemistry, Genetics and Molecular Biology-Cell Biology

CiteScore

5.80

自引率

0.00%

发文量

审稿时长

35 days

期刊介绍： Cell Regeneration aims to provide a worldwide platform for researches on stem cells and regenerative biology to develop basic science and to foster its clinical translation in medicine. Cell Regeneration welcomes reports on novel discoveries, theories, methods, technologies, and products in the field of stem cells and regenerative research, the journal is interested, but not limited to the following topics: ◎ Embryonic stem cells ◎ Induced pluripotent stem cells ◎ Tissue-specific stem cells ◎ Tissue or organ regeneration ◎ Methodology ◎ Biomaterials and regeneration ◎ Clinical translation or application in medicine

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