Universal Genetic Counseling and Testing for Black Women: A Risk-Stratified Approach to Addressing Breast Cancer Disparities.

IF 2.9 3区 医学 Q2 ONCOLOGY Clinical breast cancer Pub Date : 2024-12-04 DOI:10.1016/j.clbc.2024.11.024
Versha A Pleasant, Sofia D Merajver
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Abstract

Black women experience disproportionate breast cancer-related mortality, with similar overall incidence to White women. Approaches to address these racial health disparities should be multifaceted. Universal genetic counseling and testing for Black women could represent one dimension of a comprehensive approach in guiding early identification of those more likely to experience higher breast cancer-related mortality. The increased risk of triple-negative breast cancer and greater likelihood of early-onset breast cancer among Black women are 2 major justifications, given that these elements are already preexisting testing criteria per the National Comprehensive Cancer Network. Increasing assessment of breast cancer-related risk in the Black community through universal genetic counseling and testing should be considered to focus enhanced screening and preventive measures in a tailored risk-appropriate context.

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黑人妇女普遍遗传咨询和检测:解决乳腺癌差异的风险分层方法。
黑人妇女经历了不成比例的乳腺癌相关死亡率,总体发病率与白人妇女相似。解决这些种族健康差异的方法应该是多方面的。对黑人妇女进行普遍的遗传咨询和检测,可能是指导早期识别那些更有可能经历更高乳腺癌相关死亡率的人的综合方法的一个方面。黑人女性患三阴性乳腺癌的风险增加和早期乳腺癌的可能性增加是两个主要的理由,因为这些因素已经是国家综合癌症网络预先存在的测试标准。应考虑通过普遍的遗传咨询和检测来增加黑人社区乳腺癌相关风险的评估,以在适合风险的情况下加强筛查和预防措施。
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来源期刊
Clinical breast cancer
Clinical breast cancer 医学-肿瘤学
CiteScore
5.40
自引率
3.20%
发文量
174
审稿时长
48 days
期刊介绍: Clinical Breast Cancer is a peer-reviewed bimonthly journal that publishes original articles describing various aspects of clinical and translational research of breast cancer. Clinical Breast Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of breast cancer. The main emphasis is on recent scientific developments in all areas related to breast cancer. Specific areas of interest include clinical research reports from various therapeutic modalities, cancer genetics, drug sensitivity and resistance, novel imaging, tumor genomics, biomarkers, and chemoprevention strategies.
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