Dietary Recommendations for the Management of Gastrointestinal Symptoms in Patients Treated with GLP-1 Receptor Agonist.

IF 2.8 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Pub Date : 2024-12-19 eCollection Date: 2024-01-01 DOI:10.2147/DMSO.S494919
Silvia Gentinetta, Francesca Sottotetti, Matteo Manuelli, Hellas Cena
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Abstract

GLP-1 receptor agonist (GLP-1RA) have been developed to address the global burden of obesity and are renowned for their safety and efficacy. These medications influence hunger and satiety, reducing energy intake and promoting weight loss. Despite their benefits, GLP-1RAmay cause a slowed gastric emptying, leading to gastrointestinal symptoms. This study examines how food properties and meal composition affect these symptoms. Dietary recommendations are provided, particularly for evening meals, focusing on how different foods and nutrients can influence the rate of gastric emptying, to improve patient compliance and prevent interruption in weight loss.

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GLP-1受体激动剂治疗患者胃肠道症状的饮食建议
GLP-1受体激动剂(GLP-1RA)已被开发用于解决全球肥胖负担,并以其安全性和有效性而闻名。这些药物影响饥饿感和饱腹感,减少能量摄入,促进减肥。尽管有这些益处,glp -1可能会导致胃排空减慢,导致胃肠道症状。这项研究探讨了食物特性和膳食成分如何影响这些症状。提供了饮食建议,特别是晚餐,重点是不同的食物和营养素如何影响胃排空率,以提高患者的依从性并防止减肥中断。
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来源期刊
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
5.90
自引率
6.10%
发文量
431
审稿时长
16 weeks
期刊介绍: An international, peer-reviewed, open access, online journal. The journal is committed to the rapid publication of the latest laboratory and clinical findings in the fields of diabetes, metabolic syndrome and obesity research. Original research, review, case reports, hypothesis formation, expert opinion and commentaries are all considered for publication.
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