Zhi-Yu Zhang , Xiao-Man Fu , Yuan-Cao Shu , Xu-Jie Qin , Ying-Jun Zhang , Ping Zhao , Xiao-Qin Yang , Li-Hua Zou , Wei-Hua Wang , Guo-Lei Zhu
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引用次数: 0
Abstract
Three novel compounds, including an aromatic amino acid, dimorine A (1), a suncheonoside derivative, dimoroside A (2), and a phenylpropanoid glycoside, dimoroside B (3), together with four known compounds (4–7) were separated from Umbelopsis dimorpha VDG10, the predominant endophytic fungus found in the roots of Vaccinium dunalianum Wight (Ericaceae). Their structures were elucidated by spectroscopic methods, and the ECD spectrum confirmed the absolute configuration of 3. In addition, the antifungal activities of novel compounds against five phytopathogenic fungi were evaluated. The results indicated that compound 3 has a better inhibitory effect on Alternaria brassicicola than the broad-spectrum antifungal agent thiabendazole, and its MICs of 15.63–7.82 μg/mL.
期刊介绍:
Fitoterapia is a Journal dedicated to medicinal plants and to bioactive natural products of plant origin. It publishes original contributions in seven major areas:
1. Characterization of active ingredients of medicinal plants
2. Development of standardization method for bioactive plant extracts and natural products
3. Identification of bioactivity in plant extracts
4. Identification of targets and mechanism of activity of plant extracts
5. Production and genomic characterization of medicinal plants biomass
6. Chemistry and biochemistry of bioactive natural products of plant origin
7. Critical reviews of the historical, clinical and legal status of medicinal plants, and accounts on topical issues.