Sarcomas of the Head and Neck Region.

IF 1 4区 医学 Q3 SURGERY Journal of Craniofacial Surgery Pub Date : 2025-01-01 Epub Date: 2024-10-15 DOI:10.1097/SCS.0000000000010783
Milovan V Dimitrijević, Ana Marija M Tomić, Nikola R Todorović, Ana M Dimitrijević, Đurđina B Kablar
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Abstract

Introduction: Sarcomas are relatively rare malignant tumors of mesenchymal origin, representing only about 1% of tumors in the head and neck region.

Materials and methods: A retrospective study involved patients with sarcomas of the head and neck region who were diagnosed and treated over a 5-year period.

Results: Nine patients were included, 4 men and 5 women. The mean age of the patients was 51 years. Eight patients had soft tissue sarcomas, and 1 patient had osteosarcoma. The most common histologic types were dermatofibrosarcoma protuberans and angiosarcoma. Tumors presented predominantly with local symptomatology. All patients were treated only by surgical excision. No distant or regional metastases were found in any patient. Complete surgical excision was achieved in all cases, except in patients with chondrosarcoma of the nose and sinuses, who died due to local progression in the second year of follow-up. Other patients were disease-free during the observed period; a patient with osteosarcoma died in the fourth year of follow-up without recurrence of the malignant disease.

Conclusion: Large prospective and multicenter studies are necessary to provide relevant data on the distribution of different types of sarcoma in the head and neck region, their clinical behavior and response to therapeutic modalities, as well as on recurrence, presence of metastases, and survival.

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头颈部的肉瘤。
肉瘤是一种相对罕见的间充质恶性肿瘤,仅占头颈部肿瘤的1%左右。材料和方法:一项回顾性研究,涉及5年内诊断和治疗的头颈部肉瘤患者。结果:共纳入9例患者,男4例,女5例。患者平均年龄51岁。软组织肉瘤8例,骨肉瘤1例。最常见的组织学类型为隆突性皮肤纤维肉瘤和血管肉瘤。肿瘤主要表现为局部症状。所有患者均接受手术切除治疗。所有患者均未发现远处或局部转移。除鼻和鼻窦软骨肉瘤患者在随访第二年因局部进展而死亡外,所有病例均实现了完全手术切除。其余患者在观察期内无疾病;1例骨肉瘤患者在随访第4年死亡,无恶性肿瘤复发。结论:需要大规模的前瞻性和多中心研究来提供头颈部不同类型肉瘤的分布、临床行为和对治疗方式的反应,以及复发、转移和生存的相关数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.70
自引率
11.10%
发文量
968
审稿时长
1.5 months
期刊介绍: ​The Journal of Craniofacial Surgery serves as a forum of communication for all those involved in craniofacial surgery, maxillofacial surgery and pediatric plastic surgery. Coverage ranges from practical aspects of craniofacial surgery to the basic science that underlies surgical practice. The journal publishes original articles, scientific reviews, editorials and invited commentary, abstracts and selected articles from international journals, and occasional international bibliographies in craniofacial surgery.
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