Prevalence and impact of vasomotor symptoms due to menopause among women in Canada: A subgroup analysis from an international cross-sectional survey of Women with Vasomotor Symptoms Associated with Menopause (WARM Study).

IF 3 3区 医学 Q1 OBSTETRICS & GYNECOLOGY Menopause: The Journal of The North American Menopause Society Pub Date : 2025-01-01 DOI:10.1097/GME.0000000000002451
Nese Yuksel, Lora Todorova, Ludmila Scrine, Carol Rea, Céline Bouchard
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Abstract

Objective: The aim of the study was to assess the prevalence of postmenopausal vasomotor symptoms (VMS) and the impact of VMS and related treatment patterns among perimenopausal and postmenopausal Canadian women.

Methods: A subgroup analysis of data from a cross-sectional online survey of women aged 40-65 years conducted November 4, 2021, through January 17, 2022, evaluated the prevalence of moderate/severe VMS among postmenopausal Canadian women. The analysis also assessed survey responses from perimenopausal and postmenopausal Canadian women with moderate/severe VMS who completed the Menopause-Specific Quality of Life questionnaire, Work Productivity and Activity Impairment questionnaire, and the Patient-Reported Outcomes Measurement Information System Sleep Disturbances-Short Form 8b and answered questions about treatment patterns and attitudes toward treatments.

Results: Of 2,456 Canadian postmenopausal women, 360 (14.7%; primary analysis) reported moderate/severe VMS in the previous month. Perimenopausal and postmenopausal women with moderate/severe VMS (n = 400; secondary analysis) reported negative impact on overall quality of life (mean total Menopause-Specific Quality of Life questionnaire score: 4.3/8). VMS impaired overall work and daily activities by 30.2% and 35.7%, respectively. Overall mean (SD) Patient-Reported Outcomes Measurement Information System Sleep Disturbance-Short Form 8b score (scale 8-40) was 28.5 (6.9), confirming sleep disturbances in this population. The majority of women (88% of the total cohort) sought advice, but about half were never treated. Most women had positive or neutral attitudes toward menopause.

Conclusions: In a survey conducted in Canada, moderate/severe VMS were reported by 14.7% of postmenopausal women and were associated with impairment in quality of life, work productivity, daily activities, and sleep in perimenopausal and postmenopausal women.

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加拿大妇女绝经期血管舒缩症状的患病率和影响:来自绝经期血管舒缩症状妇女国际横断面调查(WARM研究)的亚组分析。
目的:本研究的目的是评估加拿大围绝经期和绝经后妇女绝经后血管舒缩症状(VMS)的患病率以及VMS和相关治疗模式的影响。方法:对2021年11月4日至2022年1月17日进行的40-65岁女性横断面在线调查数据进行亚组分析,评估加拿大绝经后女性中/重度VMS的患病率。分析还评估了加拿大中度/重度VMS围绝经期和绝经后妇女的调查反馈,这些妇女完成了绝经期特定生活质量问卷、工作效率和活动障碍问卷以及患者报告的结果测量信息系统睡眠障碍-短表8b,并回答了有关治疗模式和治疗态度的问题。结果:2456名加拿大绝经后妇女中,360名(14.7%;初步分析)在上个月报告中度/重度VMS。中度/重度VMS围绝经期和绝经后妇女(n = 400;二次分析)报告了对整体生活质量的负面影响(绝经特异性生活质量问卷平均总得分:4.3/8)。VMS对整体工作和日常活动的影响分别为30.2%和35.7%。患者报告结果测量信息系统睡眠障碍短表8b评分(量表8-40)的总平均值(SD)为28.5(6.9),证实该人群存在睡眠障碍。大多数女性(占总队列的88%)寻求建议,但约有一半从未接受过治疗。大多数妇女对更年期持积极或中立的态度。结论:在加拿大进行的一项调查中,14.7%的绝经后妇女报告了中度/重度VMS,并且与围绝经期和绝经后妇女的生活质量、工作效率、日常活动和睡眠受损有关。
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来源期刊
CiteScore
5.40
自引率
7.40%
发文量
330
审稿时长
3-8 weeks
期刊介绍: ​Menopause, published monthly, provides a forum for new research, applied basic science, and clinical guidelines on all aspects of menopause. The scope and usefulness of the journal extend beyond gynecology, encompassing many varied biomedical areas, including internal medicine, family practice, medical subspecialties such as cardiology and geriatrics, epidemiology, pathology, sociology, psychology, anthropology, and pharmacology. This forum is essential to help integrate these areas, highlight needs for future research, and enhance health care.
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