[Research progress in animal embryo implantation and endometrial organoids].

Q4 Biochemistry, Genetics and Molecular Biology Sheng wu gong cheng xue bao = Chinese journal of biotechnology Pub Date : 2024-12-25 DOI:10.13345/j.cjb.240128
Jingyi Tu, Changqing Shen, Ruiling Lei, Jie Yang, Shicheng Wang, Siqi Peng, Lang Li, Xiaoyan Qiu
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引用次数: 0

Abstract

Embryo implantation involves a complex interaction between the embryo and the endometrium of the mother, the study of which faces a variety of problems. The modeling of endometrial epithelial organoids and endometrial assembloids provides a new way to study the process of embryo implantation in vitro. This paper summarized the latest research progress in embryo implantation, the regulation mechanism of endometrial receptivity by estrogen- progesterone coordination and embryo-derived signals, the establishment of endometrial organoids, and the development and application of endometrial assembloids in the research on mother-embryo interaction, providing new strategies for studying the communication between embryo and maternal uterus during implantation.

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动物胚胎植入与子宫内膜类器官的研究进展
胚胎着床涉及胚胎与母体子宫内膜之间复杂的相互作用,其研究面临着各种各样的问题。子宫内膜上皮类器官和子宫内膜组装体的建模为体外研究胚胎着床过程提供了新的途径。本文综述了胚胎着床的最新研究进展、雌激素-孕激素协调和胚胎源性信号对子宫内膜容受性的调节机制、子宫内膜类器官的建立以及子宫内膜组装体在母胚相互作用研究中的发展与应用,为着床过程中胚胎与子宫间的交流研究提供了新的策略。
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来源期刊
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Sheng wu gong cheng xue bao = Chinese journal of biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
1.50
自引率
0.00%
发文量
298
期刊介绍: Chinese Journal of Biotechnology (Chinese edition) , sponsored by the Institute of Microbiology, Chinese Academy of Sciences and the Chinese Society for Microbiology, is a peer-reviewed international journal. The journal is cited by many scientific databases , such as Chemical Abstract (CA), Biology Abstract (BA), MEDLINE, Russian Digest , Chinese Scientific Citation Index (CSCI), Chinese Journal Citation Report (CJCR), and Chinese Academic Journal (CD version). The Journal publishes new discoveries, techniques and developments in genetic engineering, cell engineering, enzyme engineering, biochemical engineering, tissue engineering, bioinformatics, biochips and other fields of biotechnology.
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