Adjacent Level Canal Area Changes up to 2 years after Lumbar Spinal Stenosis Decompressive Surgery.

IF 2.6 2区 医学 Q2 CLINICAL NEUROLOGY Spine Pub Date : 2024-12-25 DOI:10.1097/BRS.0000000000005247
Helena Brisby, Tor Åge Myklebust, Hasan Banitalebi, Ivar Austevoll, Jorn Aaen, Kjersti Storheim, Christian Hellum, Eric Franssen, Kari Indrekvam, Erland Hermansen
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Abstract

Study design: A secondary analysis of data from the NORDSTEN-spinal stenosis trial (SST).

Objective: The aim of the present study was to investigate whether the dural sac cross-sectional area (DSCA) on magnetic resonance imaging (MRI) of adjacent segments decreases after decompressive surgery due to lumbar spinal stenosis (LSS) up to 2 years postoperatively, and to investigate possible associations with baseline variables, including preoperative patient and radiological characteristics, and surgical method used.

Summary of background data: Decompressive surgery for LSS is currently the most common spinal surgery procedure; however, there is limited knowledge on changes in the DSCA over time adjacent to a decompressed segment.

Methods: In the NORDSTEN-SST 437 patients were randomized to decompression with one of three minimally invasive surgical methods for LSS. The patients underwent MRI of the lumbar spine (L2-L5) before surgery and at 3 and 24 months postoperatively. Descriptive statistics of adjacent DSCA and changes in adjacent DSCA are presented. Possible prognostic factors (preoperative factors, radiological measures, and surgical method) for changes in the adjacent DSCA were examined using multivariate regression analyses.

Results: 322 patients (74%) in the original NORDSTEN-SST had undergone MRI at both 3 and 24 months postoperatively and were included (360 adjacent levels, 263 cranial, and 97 caudal to a decompressed level). Up to 2 years postoperatively, no decrease in adjacent DSCA was observed. No associations were found between the investigated baseline variables, and DSCA change from 0 to 2 years, except for a weak association with baseline adjacent DSCA.

Conclusion: Up to 2 years postoperatively, the DSCA did not decrease at adjacent levels after decompressive surgery. None of the investigated baseline variables showed any clinical meaningful prognostic value regarding adjacent DSCA changes 2 years postoperatively. The findings support previous reports that decompression of adjacent levels is not required to prevent subsequent stenosis.

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腰椎管狭窄减压手术后2年内邻近水平椎管面积的变化。
研究设计:对nordsten -椎管狭窄试验(SST)数据进行二次分析。目的:本研究的目的是探讨腰椎管狭窄症(LSS)术后2年内邻近节段的磁共振成像(MRI)硬膜囊横截面积(DSCA)是否减少,并探讨其与基线变量(包括术前患者和放射学特征以及手术方法)的可能关联。背景资料总结:LSS的减压手术是目前最常见的脊柱外科手术;然而,关于减压段附近的DSCA随时间变化的知识有限。方法:在NORDSTEN-SST中,437例患者随机接受三种微创手术方法中的一种减压治疗LSS。术前、术后3个月和24个月对患者腰椎(L2-L5)进行MRI检查。给出了相邻DSCA的描述性统计和相邻DSCA的变化。使用多变量回归分析检查邻近DSCA改变的可能预后因素(术前因素、放射学措施和手术方法)。结果:322例(74%)原始NORDSTEN-SST患者在术后3个月和24个月接受了MRI检查(360例相邻节段,263例颅脑节段,97例尾侧减压节段)。术后2年,未观察到相邻DSCA下降。调查的基线变量与0 - 2年的DSCA变化之间没有关联,除了与基线相邻DSCA有弱关联。结论:术后2年,减压手术后相邻水平的DSCA均未下降。所有研究的基线变量均未显示术后2年相邻DSCA变化的任何临床有意义的预后价值。该研究结果支持了先前的报道,即相邻节段不需要减压来预防随后的狭窄。
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来源期刊
Spine
Spine 医学-临床神经学
CiteScore
5.90
自引率
6.70%
发文量
361
审稿时长
6.0 months
期刊介绍: Lippincott Williams & Wilkins is a leading international publisher of professional health information for physicians, nurses, specialized clinicians and students. For a complete listing of titles currently published by Lippincott Williams & Wilkins and detailed information about print, online, and other offerings, please visit the LWW Online Store. Recognized internationally as the leading journal in its field, Spine is an international, peer-reviewed, bi-weekly periodical that considers for publication original articles in the field of Spine. It is the leading subspecialty journal for the treatment of spinal disorders. Only original papers are considered for publication with the understanding that they are contributed solely to Spine. The Journal does not publish articles reporting material that has been reported at length elsewhere.
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