Validation of the Nottingham Hip Fracture Score (NHFS) to predict 30-day mortality following hip fracture in a Mexican population

Mayra Arely Serrano-Lugo , Iván Luján-Hernández , Ma. Elena Ledesma-González , Quitzia Libertad Torres-Salazar
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Abstract

Introduction

Hip fractures in the elderly pose a significant clinical challenge, with high short-term mortality rates. The Nottingham Hip Fracture Score (NHFS) has proven useful in predicting 30-day mortality in European and Asian populations, but its validity in the Mexican population has not been widely assessed.

General objective

To validate the NHFS in predicting 30-day mortality following hip fracture in a Mexican population.

Methodology

An observational, longitudinal, and prospective study was conducted with 143 patients over 60 years of age with hip fractures treated surgically at Hospital General de Zona No. 16 of IMSS. NHFS was applied upon admission, and health status was verified 30 days post-surgery. The area under the ROC curve (AUC), sensitivity, specificity, and model calibration were calculated.

Results

The 30-day mortality rate was 14.7%. The NHFS had an AUC of 0.72, indicating moderate predictive capacity. A cutoff score of 3.5 yielded 85.7% sensitivity and 24% specificity. A higher cutoff of 4.5 improved specificity (45%) but reduced sensitivity (81%).

Conclusions

The NHFS is a useful tool for predicting 30-day mortality in the Mexican population with hip fractures, though its discriminative ability is moderate. A 3.5 cutoff is recommended when prioritizing sensitivity in clinical settings.
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诺丁汉髋部骨折评分(NHFS)预测墨西哥人群髋部骨折后30天死亡率的验证。
老年人髋部骨折具有很高的短期死亡率,是一个重大的临床挑战。诺丁汉髋部骨折评分(NHFS)在预测欧洲和亚洲人群的30天死亡率方面已被证明是有用的,但其在墨西哥人群中的有效性尚未得到广泛评估。总体目的:验证NHFS在预测墨西哥人群髋部骨折后30天死亡率中的作用。方法:对143例60岁以上髋部骨折患者在IMSS第16总医院进行了一项观察性、纵向和前瞻性研究。入院时进行NHFS,术后30天进行健康状况验证。计算ROC曲线下面积(AUC)、灵敏度、特异度和模型校准。结果:30天死亡率为14.7%。NHFS的AUC为0.72,预测能力中等。临界值为3.5,敏感性为85.7%,特异性为24%。4.5的较高临界值提高了特异性(45%),但降低了敏感性(81%)。结论:NHFS是预测墨西哥髋部骨折患者30天死亡率的有用工具,但其判别能力较弱。在临床环境中对敏感性进行优先排序时,推荐3.5的临界值。
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来源期刊
Revista Espanola de Geriatria y Gerontologia
Revista Espanola de Geriatria y Gerontologia Medicine-Medicine (miscellaneous)
CiteScore
1.90
自引率
0.00%
发文量
62
审稿时长
85 days
期刊介绍: Una revista de gran prestigio por sus artículos originales de investigación y revisiones. Permite cubrir todas las áreas de la medicina pero siempre desde la atención al paciente anciano, y está presente en los más reconocidos índices internacionales.
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