SEROUS RETINAL DETACHMENT DUE TO CRYPTOCOCCOSIS IN AN IMMUNOCOMPETENT PATIENT.

Q3 Medicine Retinal Cases and Brief Reports Pub Date : 2025-11-01 DOI:10.1097/ICB.0000000000001657

Anna Carolina Carvalho Araujo, Isadora L Said, Bruna Moussallem, Arnaldo F Bordon

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Abstract

Purpose: The objective of this study was to report a case of bilateral ocular cryptococcosis in an immunocompetent patient without neurologic findings.

Methods: This was a case report.

Results: A 30-year-old healthy White man presented with painless blurred vision in the left eye. Examination showed bilateral serous detachments and white retinal lesions. The visual acuity was 20/40 in the right eye and hand motions in the left eye. Neurologic workup and serologies were negative, and a computer tomography-positron emission tomography scan showed diffuse lymph node enlargement with metabolic activity and a suspected lymphoproliferative disorder. The myelogram and immunohistochemistry were normal. A biopsy of the cervical lymph nodes was positive for Cryptococcus neoformans . He was treated with antifungal medications and had complete resolution of the subretinal fluid and visual acuity improvement.

Conclusions: Cryptococcosis is a rare entity in an immunocompetent person. A systemic workup is necessary to diagnose cryptococcosis and initiate prompt treatment.

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免疫功能正常患者隐球菌病所致浆液性视网膜脱离。

目的：报告一例免疫功能正常且无神经系统病变的双侧眼隐球菌病。方法：病例报告。结果：一名30岁的健康白人男性表现为左眼无痛性视力模糊。检查显示双侧浆液性脱离和白色视网膜病变。右眼视力（VA）为20/40，左眼手部运动正常。神经系统检查和血清学均为阴性，计算机断层扫描-正电子发射断层扫描显示弥漫性淋巴结肿大伴代谢活动和疑似淋巴增生性疾病。骨髓图和免疫组化检查均正常。颈部淋巴结活检呈新型隐球菌阳性。他接受了抗真菌药物治疗，视网膜下积液完全消失，VA得到改善。结论：隐球菌病在免疫正常人群中是一种罕见的疾病。系统检查是诊断隐球菌病和开始及时治疗的必要条件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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