Photodynamic Therapy as a Future Method in the Treatment of Parotid Gland Tumor: A Review.

Lidia Bieniasz, Wojciech Domka, David Aebisher, Dorota Bartusik-Aebisher
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Abstract

Photodynamic therapy (PDT) is emerging as a promising treatment for many diseases. This non-invasive approach uses photosensitizing agents and light to selectively destroy abnormal cells, providing a valuable alternative to traditional treatments. Scientists are investigating the use of PDT in various areas of the head, and their work is focused on a growing number of new discoveries and methods for treating cancer. We have analyzed the use of photodynamic therapy in the treatment of head and neck cancer (HNC) and present the latest advances in this field, with particular emphasis on its effectiveness in improving the long-term quality of life of patients with HNC. The effectiveness of PDT in the treatment of cancer depends largely on the depth of the tumor location. PDT is particularly useful in the treatment of early diagnosed cancers and superficial tumors. Many head and neck tumors are ideal candidates for this therapy due to the possibility of precise assessment of the lesions and the provision of adequate irradiation in these locations. PDT is currently considered a revolutionary, modern form of cancer therapy. A significant advantage of PDT is that cells do not develop resistance to singlet oxygen, which makes this method extremely effective. Although this method is safe, the limited depth of light penetration limits its use in the treatment of advanced stages of cancer.

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光动力疗法作为治疗腮腺肿瘤的未来方法:综述。
光动力疗法(PDT)是一种有前景的治疗多种疾病的方法。这种非侵入性方法使用光敏剂和光选择性地破坏异常细胞,为传统治疗提供了一种有价值的替代方法。科学家们正在研究PDT在头部不同区域的应用,他们的工作重点是越来越多的新发现和治疗癌症的方法。我们分析了光动力疗法在头颈癌(HNC)治疗中的应用,并介绍了该领域的最新进展,特别强调了其在改善HNC患者长期生活质量方面的有效性。PDT治疗癌症的有效性在很大程度上取决于肿瘤位置的深度。PDT在治疗早期诊断的癌症和浅表肿瘤方面特别有用。许多头颈部肿瘤是这种治疗的理想候选者,因为可以精确评估病变,并在这些部位提供足够的照射。PDT目前被认为是一种革命性的现代癌症治疗形式。PDT的一个显著优点是细胞不会对单线态氧产生抗性,这使得该方法非常有效。虽然这种方法是安全的,但光线穿透的深度有限,限制了它在晚期癌症治疗中的应用。
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