Comparison of functional, structural and vascular characteristics between dominant and nondominant eyes.

IF 2.6 4区医学 Q2 OPHTHALMOLOGY Documenta Ophthalmologica Pub Date : 2025-02-01 Epub Date: 2024-12-29 DOI:10.1007/s10633-024-10001-2

Mualla Hamurcu, Burcu Polat Gültekin, Melisa Tuncer Göçmen, Zarife Nurbanu Mendi

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Abstract

Purpose: The aim of this study was to compare retinal and optic disc functions as well as vascular structures in dominant eyes (DE) and non-dominant eyes (NDE) among healthy adults using pattern electroretinogram (PERG), optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) tests.

Methods: Seventy-two eyes of 36 healthy subjects with bilateral visual acuity of 1.0 were included. Parameters such as intraocular pressure (IOP), cycloplegic spherical equivalent value (SE), PERG, retinal nerve fiber layer (RNFL) thicknesses and OCTA measurements were evaluated. Ocular dominance was determined using the hole-in-the-card test.

Results: Of the participants, 67% were female, with a median age of 28 (min-max.18-35) years. Right eye dominance was observed in 61.2% of cases, while left eye dominance was seen in 38.8%. There was no significant difference in refractive values between eyes with right and left eye dominance (0.60 ± 0.40 and 0.41 ± 0.28, p = 0.42). The dominant eyes showed significantly higher P50 amplitude (10.2 µV vs. 9.2 µV, p = 0.003) and shorter peak time (47.9 ms. vs. 48.6 ms, p = 0.01) when compared to the nondominant eyes. There were comparable values in the peak times and amplitudes of the N95 component between the dominant and nondominant eyes. The RNFL layer was thicker on average (p, 0.001) as well as in the nasal and inferior quadrants of the dominant eyes (p < 0.05). OCTA analysis revealed no significant differences in the peripapillary and macular capillary vascular densities between dominant and nondominant eyes (p > 0.05), except for the deep whole capillary density in the macula, which was significantly higher in the dominant eyes (p = 0.02).

Conclusion: Our results indicate the existence of functional and structural relationships related to ocular dominance. Future studies provide further insights into ocular dominance and its relationship with eye structure.

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优势眼和非优势眼的功能、结构和血管特征比较。

目的：本研究的目的是通过视网膜电图（PERG）、光学相干断层扫描（OCT）和光学相干断层扫描血管造影（OCTA）测试，比较健康成人优势眼（DE）和非优势眼（NDE）的视网膜和视盘功能以及血管结构。方法：选取双侧视力1.0的健康受试者36例72眼。评估眼压（IOP）、睫状体麻痹球当量（SE）、PERG、视网膜神经纤维层（RNFL）厚度、OCTA测量等参数。眼优势是通过卡片入洞测试来确定的。结果：参与者中，67%为女性，中位年龄为28岁（最小-最大18-35岁）。右眼优势占61.2%，左眼优势占38.8%。左眼优势眼和右眼优势眼的屈光值差异无统计学意义（0.60±0.40和0.41±0.28,p = 0.42）。优势眼的P50振幅显著高于非优势眼（10.2µV vs. 9.2µV, p = 0.003），峰值时间显著低于非优势眼（47.9 ms vs. 48.6 ms, p = 0.01）。优势眼和非优势眼N95分量的峰值时间和振幅具有可比性。RNFL层平均较厚（p, 0.001），除黄斑深层毛细血管密度显著高于优势眼（p = 0.02）外，优势眼鼻和下象限的RNFL层均较厚（p, 0.05）。结论：我们的研究结果表明存在与眼优势相关的功能和结构关系。未来的研究将进一步深入了解眼优势及其与眼睛结构的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Documenta Ophthalmologica 医学-眼科学

CiteScore

3.50

自引率

21.40%

发文量

审稿时长

>12 weeks

期刊介绍： Documenta Ophthalmologica is an official publication of the International Society for Clinical Electrophysiology of Vision. The purpose of the journal is to promote the understanding and application of clinical electrophysiology of vision. Documenta Ophthalmologica will publish reviews, research articles, technical notes, brief reports and case studies which inform the readers about basic and clinical sciences related to visual electrodiagnosis and means to improve diagnosis and clinical management of patients using visual electrophysiology. Studies may involve animals or humans. In either case appropriate care must be taken to follow the Declaration of Helsinki for human subject or appropriate humane standards of animal care (e.g., the ARVO standards on Animal Care and Use).