Dosimetric Evaluation of Different Algorithms on Heterogeneous Slab Phantom Using CMS XiO and MONACO Treatment Planning System for 4MV, 6MV and 15MV Beam Energy: An Institutional Study.

Ajay Katake, Lalit Kumar, Balbir Singh, Nijun Mishra, Pradeep Gurjar, Rajesh Vashistha, Deepak Basandrai
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Abstract

Aim: To study the dosimetric behavior of dose computational algorithms in inhomogeneous medium using CMS XiO and MONACO treatment planning system (TPS) for 4 megavoltage (MV), 6 MV and 15 MV photon beam energies.

Material and methods: Styrofoam blocks of thickness 1.90 cm, 3.8 cm and 5.70 cm was used to introduce inhomogeneity in a slab phantom. Wipro GE computed tomography (CT) scanner was used to scan the phantom. Doses were computed on the central axis of the beam using convolution (C), superposition (S), fast superposition (FS), collapsed cone convolution (CCC) and monte carlo (MC) algorithms for field geometries of 5x5 cm2 and 10x10 cm2 for above said photon beam energies, respectively. An Ion chamber (IC) of 0.6 cc volume was used for the dose measurements. The deviation between measured and TPS computed doses were recorded.

Results: The PDD (Percentage depth dose) data obtained from the TPS (calculated data) and LINAC (measured data) was used for comparison based on different algorithms in order to calculate the percentage of maximum deviation (PMD). The PMD in MC algorithm were calculated for field sizes of 5x5 cm2 and 10x10 cm2 are found to be in ranging from 0.73% to -4.49% for 4MV,  1.62% to -2.42% for 6MV and 4.53% to -1.47%  for 15 MV for 1.90 cm air gap, 2.21% to -3.75% for 4MV, 3.87% to -2.88% for 6 MV and 4.87% to -3.46%  for 15 MV for 3.80 cm air gap, 2.77% to -4.66% for 4MV, 3.87% to -2.86% for 6 MV and 5.66% to -4.92% for 15 MV for 5.70cm air gap which is less as compared to CCC, C, FS, and S algorithms.

Conclusion: The comparison of C, S, FS, CCC and MC algorithms demonstrated that MC having better agreement with IC measurements. In conclusion, MC is a superior option for dose computation, particularly in the presence of low-density heterogeneities.

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利用CMS XiO和MONACO治疗计划系统对4MV、6MV和15MV光束能量进行不同算法的剂量学评价
目的:研究4兆、6兆、15兆光子束流能量下,CMS XiO和MONACO处理计划系统(TPS)在非均匀介质中剂量计算算法的剂量学行为。材料和方法:采用厚度分别为1.90 cm、3.8 cm和5.70 cm的泡沫聚苯乙烯块,在板坯模体中引入不均匀性。使用Wipro GE计算机断层扫描(CT)扫描仪扫描幻肢。使用卷积(C)、叠加(S)、快速叠加(FS)、塌锥卷积(CCC)和蒙特卡罗(MC)算法分别在光束的中轴线上计算上述光子束能量为5x5 cm2和10x10 cm2的场几何形状的剂量。剂量测量采用体积为0.6 cc的离子室(IC)。记录测量剂量与TPS计算剂量之间的偏差。结果:利用TPS(计算数据)和LINAC(测量数据)得到的PDD (Percentage depth dose)数据,基于不同算法进行比较,计算最大偏差百分比(PMD)。MC算法计算领域的PMD大小5 x5 cm2和10 x10 cm2发现4 MV从0.73%到-4.49%不等,1.62%至-2.42%为6 MV和4.53%至-1.47%为15 MV气隙1.90厘米,2.21%至-3.75%为4 MV, 6 MV 3.87%到-2.88%和4.87%到-3.46%为15 MV气隙3.80厘米,2.77%至-4.66%为4 MV, 6 MV 3.87%到-2.86%和5.66%到-4.92%为15 MV 5.70厘米气隙少CCC相比,C、f和S算法。结论:C、S、FS、CCC和MC算法的比较表明,MC算法与IC测量值具有较好的一致性。总之,MC是剂量计算的一个优越选择,特别是在存在低密度异质性的情况下。
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来源期刊
CiteScore
2.80
自引率
0.00%
发文量
779
审稿时长
3 months
期刊介绍: Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation. The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally. The APJCP publishes original research results under the following categories: -Epidemiology, detection and screening. -Cellular research and bio-markers. -Identification of bio-targets and agents with novel mechanisms of action. -Optimal clinical use of existing anti-cancer agents, including combination therapies. -Radiation and surgery. -Palliative care. -Patient adherence, quality of life, satisfaction. -Health economic evaluations.
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