Salvatore Chirumbolo , Marianno Franzini , Luigi Valdenassi
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引用次数: 0
Abstract
The action of ozone in medicine is a subject of interest and lively, controversial debates. Its mechanisms of action are still far from fully understood. However, it is possible that ozone triggers a series of dynamics in living organisms related to chaos, multi-stable phenomena, and oscillatory processes. Ozone may be involved in adaptive chaos. Adaptive chaos in health and the reduction of complexity in pathology are interconnected phenomena that describe the functional dynamics of biological systems. Adaptive chaos refers to a state of controlled, complex, and flexible behaviour exhibited by healthy biological systems. It allows for a dynamic balance between order and unpredictability, enabling the system to respond to various internal and external stimuli. In pathological states, the system loses its adaptive chaos, often becoming either too rigid or overly chaotic. This reduction in complexity limits the ability of the system to respond effectively to stimuli, making it prone to dysfunction. This paper addresses the role of ozone in these scenarios.
期刊介绍：
International Immunopharmacology is the primary vehicle for the publication of original research papers pertinent to the overlapping areas of immunology, pharmacology, cytokine biology, immunotherapy, immunopathology and immunotoxicology. Review articles that encompass these subjects are also welcome.
The subject material appropriate for submission includes:
• Clinical studies employing immunotherapy of any type including the use of: bacterial and chemical agents; thymic hormones, interferon, lymphokines, etc., in transplantation and diseases such as cancer, immunodeficiency, chronic infection and allergic, inflammatory or autoimmune disorders.
• Studies on the mechanisms of action of these agents for specific parameters of immune competence as well as the overall clinical state.
• Pre-clinical animal studies and in vitro studies on mechanisms of action with immunopotentiators, immunomodulators, immunoadjuvants and other pharmacological agents active on cells participating in immune or allergic responses.
• Pharmacological compounds, microbial products and toxicological agents that affect the lymphoid system, and their mechanisms of action.
• Agents that activate genes or modify transcription and translation within the immune response.
• Substances activated, generated, or released through immunologic or related pathways that are pharmacologically active.
• Production, function and regulation of cytokines and their receptors.
• Classical pharmacological studies on the effects of chemokines and bioactive factors released during immunological reactions.
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