Evaluation of Socio-Demographic Profile, Biochemical Parameters and Etiology of End Stage Renal Disease Patients in a Tertiary Care Hospital of Bangladesh.

Mymensingh medical journal : MMJ Pub Date : 2025-01-01
S R Khan, A S Roy, R D Gupta, M Asadujjaman, M B Hossain, N H Nira, J Ara, B K Saha
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Abstract

Globally the incidence and prevalence of chronic kidney disease (CKD) is increasing day by day. Various biochemical and hematological abnormalities are associated with CKD that leads to morbidity and mortality. The aim of this observational study was to evaluate the socio-demographic profile, biochemical and hematological parameters of chronic kidney disease patients in Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2020 to December 2020. This study also showed variation of biochemical parameters with lower calcium and hemoglobin level which was due to improper renal function. A total of 179 End Stage Renal Disease (ESRD) patients were enrolled in this study. Male and female ratio was 2.086:1. This study had more male patients than female. The Mean±SD age of the patient was 46.14±14.25 years and maximum of the CKD patients belonged to the age group of 41-60 years. This study depicted Glomerulonephritis was the leading cause of CKD. Second common cause was Diabetes mellitus. A portion of CKD was unknown etiology (CKDu) which was found 17.31%. Routine biochemical parameters were also seen in this study. This study showed that the majority of the patients were living below the level of poverty and came from rural area. This study aimed to evaluate the derangements of serum biochemical parameter and the association of risk factors with CKD. These demographic character, biochemical profile and etiology have association with CKD progression. So, early evaluation of these parameters may reduce the incidence of CKD.

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孟加拉国某三级医院终末期肾病患者的社会人口特征、生化参数和病因学评价
在全球范围内,慢性肾脏疾病(CKD)的发病率和患病率日益增加。各种生化和血液学异常与CKD相关,导致发病率和死亡率。本观察性研究的目的是评估2020年1月至2020年12月孟加拉国Mymensingh医学院医院慢性肾病患者的社会人口统计学特征、生化和血液学参数。本研究还发现,由于肾功能不正常,钙和血红蛋白水平降低,生化参数也会发生变化。共有179名终末期肾病(ESRD)患者参加了这项研究。男女比例为2.086:1。这项研究的男性患者多于女性患者。患者的平均±SD年龄为46.14±14.25岁,最大的CKD患者属于41-60岁年龄组。本研究表明肾小球肾炎是CKD的主要原因。第二常见的原因是糖尿病。病因不明(CKDu)占17.31%。常规生化参数也见于本研究。研究表明,大多数患者生活在贫困水平以下,来自农村地区。本研究旨在探讨CKD患者血清生化指标紊乱及危险因素与CKD的关系。这些人口统计学特征、生化特征和病因学与CKD进展有关。因此,早期评估这些参数可能会降低CKD的发病率。
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