Status of Serum Magnesium among Patients with Chronic Kidney Disease.

Abstract

Chronic kidney disease (CKD) is one of the largest public health issues and the major cause of death worldwide. Due to an increase in the incidence of systemic diseases like diabetes and hypertension, which are the two main causes of CKD and kidney damage, the prevalence of CKD is rising globally. Chronic Kidney Disease results in mineral disorders as well as profound lipid disorders due to improper balancing of the mineral & hormone levels in the body. This cross-sectional study was completed in the Department of Biochemistry, Mymensingh Medical College, in collaboration with the Department of Nephrology, Mymensingh Medical College Hospital, during the period of July 2022 to June 2023. The subjects were selected based on inclusion and exclusion criteria by purposive non-random sampling. Total 120 subjects were included in this study. Out of them, 60 were selected chronic kidney disease patient (Group II) and another 60 apparently normal healthy persons were selected as control (Group I). In this study, serum magnesium levels were measured for analytical study. All the values were demonstrated as mean±SD and values of serum magnesium were in Group I (1.99±0.50 mg/dl) and in Group II (2.24±0.19 mg/dl). Statistical analysis was performed using by statistical package for social science (SPSS) version 26.0. The statistical significance of the difference between the case and control was evaluated using Student's unpaired 't'-test (p<0.001). After careful evaluation, this study was found that mean serum magnesium levels was significantly increased in CKD patients.