Clinical efficacy of tobramycin dexamethasone eye ointment combined with a catheter in endoscopic dacryocystorhinostomy.

IF 1.1 4区医学 Q3 OTORHINOLARYNGOLOGY Journal of Laryngology and Otology Pub Date : 2024-10-21 DOI:10.1017/S0022215124001622

Hailin Hu, Xiaoping Bi, Yimin Li, Junfang Wang, Wodong Shi

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Abstract

Objective: To evaluate the clinical efficacy of tobramycin dexamethasone eye ointment combined with a catheter in endoscopic dacryocystorhinostomy.

Methods: Eighty chronic dacryocystitis patients were randomly divided into two groups: observation (n = 39) and control (n = 41). Both groups underwent endoscopic dacryocystorhinostomy. The observation group used tobramycin dexamethasone eye ointment and catheter support, while the control group used only the eye ointment.

Results: No statistical differences were found in gender, age, disease course or eye type. However, the anastomotic formation time and bleeding amount were significantly different between the two groups (p < 0.001). After six months of follow up, there were no significant complications differences (p > 0.05). The fluorescein disappearance test time in the observation group was significantly shorter (p < 0.001), and the clinical effective rate was significantly higher (97.4 per cent vs 78 per cent, p < 0.05) in the observation group.

Conclusion: Using tobramycin dexamethasone eye ointment combined with a catheter slightly prolongs the operation time and increases bleeding, but promotes anastomotic healing, accelerates tear drainage, improves the operation success rate and is economically efficient.

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妥布霉素地塞米松眼膏联合导管在内镜下泪囊鼻腔造瘘术中的临床疗效。

目的：评价妥布霉素地塞米松眼膏联合导管在内镜下泪囊鼻腔造瘘术中的临床疗效。方法：80例慢性泪囊炎患者随机分为观察组（n = 39）和对照组（n = 41）。两组均行内窥镜泪囊鼻腔造口术。观察组使用妥布霉素地塞米松眼膏加导管支持，对照组仅使用妥布霉素地塞米松眼膏。结果：性别、年龄、病程、眼型差异无统计学意义。两组吻合口形成时间及出血量差异有统计学意义（p < 0.001）。随访6个月，两组并发症发生率无明显差异（p < 0.05）。观察组荧光素消失试验时间显著缩短（p < 0.001），临床有效率显著高于观察组（97.4% vs 78%, p < 0.05）。结论：妥布霉素地塞米松眼膏联合导管使用，手术时间略延长，出血量增加，但能促进吻合口愈合，加速泪液引流，提高手术成功率，经济有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Laryngology and Otology 医学-耳鼻喉科学

CiteScore

3.20

自引率

11.80%

发文量

593

审稿时长

3-6 weeks

期刊介绍： The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.