Generation of a human induced pluripotent stem cell line NTUHi006-A from a polycystic ovarian syndrome patient

IF 0.8 4区 医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Stem cell research Pub Date : 2025-02-01 DOI:10.1016/j.scr.2024.103647
Chia-Eng Wu , Hsiang-Po Huang , Hong-Nerng Ho , Mei-Jou Chen
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引用次数: 0

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to multifactors and genetic polymorphisms. Here, we derived an induced pluripotent stem cell (hiPSC) line NTUHi006-A from a phenotype A (full-blown) PCOS patients with clinical hyperandrogenism, chronic anovulation, and polycystic ovarian morphology on ultrasonography. NTUHi006-A showed stemness, pluripotency and stem cell-like morphology.
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多囊卵巢综合征患者诱导多能干细胞NTUHi006-A的生成
多囊卵巢综合征(PCOS)是一种常见的内分泌疾病,与多因素和遗传多态性有关。在这里,我们从临床雄激素分泌过多、慢性无排卵、超声表现为多囊卵巢的a型(全面型)PCOS患者中获得了诱导多能干细胞(hiPSC)细胞系NTUHi006-A。NTUHi006-A具有干性、多能性和干细胞样形态。
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来源期刊
Stem cell research
Stem cell research 生物-生物工程与应用微生物
CiteScore
2.20
自引率
8.30%
发文量
338
审稿时长
55 days
期刊介绍: Stem Cell Research is dedicated to publishing high-quality manuscripts focusing on the biology and applications of stem cell research. Submissions to Stem Cell Research, may cover all aspects of stem cells, including embryonic stem cells, tissue-specific stem cells, cancer stem cells, developmental studies, stem cell genomes, and translational research. Stem Cell Research publishes 6 issues a year.
期刊最新文献
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