{"title":"[Methotrexate therapy for primary intraocular lymphoma: a case report].","authors":"Q Wang, F Zeng, C Wei","doi":"10.3760/cma.j.cn112142-20240308-00102","DOIUrl":null,"url":null,"abstract":"<p><p>A 63-year-old male patient presented with a four-month history of vision loss in the left eye and blurred vision in the right eye, the cause of which was not immediately apparent. The patient was initially diagnosed with uveitis in both eyes at the Department of Ophthalmology. Subsequently, the patient was diagnosed as central nervous system lymphoma at the Department of Brain Medicine and initiated a systemic treatment. However, due to the progressive deterioration of visual function, a further evaluation was performed at the Department of Ophthalmology. Based on the results of the vitreous fluid cytokine test, intraocular lymphoma was diagnosed in both eyes. Intravitreal methotrexate injections were administered for eight times and a notable improvement in visual acuity was achieved in both eyes.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"61 1","pages":"61-64"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华眼科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/cma.j.cn112142-20240308-00102","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
A 63-year-old male patient presented with a four-month history of vision loss in the left eye and blurred vision in the right eye, the cause of which was not immediately apparent. The patient was initially diagnosed with uveitis in both eyes at the Department of Ophthalmology. Subsequently, the patient was diagnosed as central nervous system lymphoma at the Department of Brain Medicine and initiated a systemic treatment. However, due to the progressive deterioration of visual function, a further evaluation was performed at the Department of Ophthalmology. Based on the results of the vitreous fluid cytokine test, intraocular lymphoma was diagnosed in both eyes. Intravitreal methotrexate injections were administered for eight times and a notable improvement in visual acuity was achieved in both eyes.