[Peptide regulation of cellular aging.]

Abstract

Cellular aging is the inability of structures to proliferate (further division) and repair damage while maintaining metabolic activity. The key well-known factors of cellular aging are the processes of DNA damage, telomere shortening, the development of oxidative stress and epigenetic changes. The above factors provoke the development of a pro-inflammatory environment, leading to errors in gene expression and metabolic dysregulation, thereby affecting the development of age-related diseases that contribute to pathological changes in the functions of tissues and organs. Modern pharmacotherapy approaches aimed at slowing down the processes of cellular aging are mainly focused on three key strategies: influencing the signaling pathways that cause cellular aging, as well as specific factors of the cell cycle (protein structures - receptors, carrier proteins, bioregulators, and so on), improving the elimination of cellular debris by the immune systern pharmacotherapy approaches aimed at slowing down the processes of cellular aging are mainly focused on three key strategies: influencing the signaling pathways that cause cellular aging, as well as specific factors of the cell cycle (protein structures - receptors, carrier proteins, bioregulators, and so on), improving the elimination of cellular debris by the immune system. In the elderly, the regulation of various processes of the cell cycle is disrupted, and the use of polypeptide complexes helps to maintain normal body functions by stimulating the synthesis of proteins-markers of cell functional activity.