[Retracted] Differential effects of PXD101 (belinostat) on androgen-dependent and androgen-independent prostate cancer models.

IF 4.5 3区 医学 Q1 ONCOLOGY International journal of oncology Pub Date : 2025-02-01 Epub Date: 2025-01-03 DOI:10.3892/ijo.2025.5717
Giovanni Luca Gravina, Francesco Marampon, Ilaria Giusti, Eleonora Carosa, Stefania Di Sante, Enrico Ricevuto, Vincenza Dolo, Vincenzo Tombolini, Emmanuele A Jannini, Claudio Festuccia
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Abstract

Following the publication of the above article, a concerned reader drew to the Editor's attention that certain of the western blot assay data shown in Fig. 4G on p. 717 were strikingly similar to data that had appeared in a paper published previously in the journal Molecular Cancer Therapeutics, which had been written by different authors at different research institutes. Moreover, there appeared to be as many as five sets of duplicated protein bands in Fig. 4B and C, including the appearance of apparently the same protein band in different orientations in Fig. 4C in one case, and certain data shown in Fig. 4B and G had apparently been re-used in these figure parts. After having performed an independent assessment of these issues in the Editorial Office, these concerns of the reader were found to have been validated; therefore, the Editor of International Journal of Oncology has decided that this paper should be retracted from the publication. After having been in contact with the authors, they accepted the decision to retract the paper. The corresponding author, Claudio Festuccia, takes full responsibility for the raised concerns and clarifies that the other co-authors were not directly involved in the preparation of the submitted figures. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Oncology 40: 711-720, 2012; DOI: 10.3892/ijo.2011.1270].

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【撤回】PXD101 (belinostat)对雄激素依赖性和非雄激素依赖性前列腺癌模型的差异影响。
在上述文章发表后,一位关心的读者提请编辑注意,第717页图4G中所示的某些western blot分析数据与之前发表在《分子癌症治疗学》杂志上的一篇论文中的数据惊人地相似,该论文由不同研究机构的不同作者撰写。此外,在图4B和C中出现了多达5组重复的蛋白质条带,其中有一例在图4C中出现了明显相同的蛋白质条带,但方向不同,图4B和G中显示的某些数据在这些图部分明显被重复使用。在编辑部对这些问题进行独立评估后,发现读者的这些担忧得到了验证;因此,《国际肿瘤学杂志》的编辑决定撤回这篇论文。在与作者联系后,他们接受了撤回论文的决定。通讯作者Claudio Festuccia对所引起的关切负全部责任,并澄清其他共同作者没有直接参与编制所提交的数据。对于由此给读者带来的不便,本刊编辑深表歉意。[j]国际肿瘤学杂志,2012;DOI: 10.3892 / ijo.2011.1270]。
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来源期刊
CiteScore
9.60
自引率
0.00%
发文量
157
审稿时长
2.1 months
期刊介绍: The main aim of Spandidos Publications is to facilitate scientific communication in a clear, concise and objective manner, while striving to provide prompt publication of original works of high quality. The journals largely concentrate on molecular and experimental medicine, oncology, clinical and experimental cancer treatment and biomedical research. All journals published by Spandidos Publications Ltd. maintain the highest standards of quality, and the members of their Editorial Boards are world-renowned scientists.
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