A data-driven approach to study temporal characteristics of COVID-19 infection and death Time Series for twelve countries across six continents.

IF 3.9 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES BMC Medical Research Methodology Pub Date : 2025-01-03 DOI:10.1186/s12874-024-02423-y
Sabyasachi Guharay
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Abstract

Background: In this work, we implement a data-driven approach using an aggregation of several analytical methods to study the characteristics of COVID-19 daily infection and death time series and identify correlations and characteristic trends that can be corroborated to the time evolution of this disease. The datasets cover twelve distinct countries across six continents, from January 22, 2020 till March 1, 2022. This time span is partitioned into three windows: (1) pre-vaccine, (2) post-vaccine and pre-omicron (BA.1 variant), and (3) post-vaccine including post-omicron variant. This study enables deriving insights into intriguing questions related to the science of system dynamics pertaining to COVID-19 evolution.

Methods: We implement a set of several distinct analytical methods for: (a) statistical studies to estimate the skewness and kurtosis of the data distributions; (b) analyzing the stationarity properties of these time series using the Augmented Dickey-Fuller (ADF) tests; (c) examining co-integration properties for the non-stationary time series using the Phillips-Ouliaris (PO) tests; (d) calculating the Hurst exponent using the rescaled-range (R/S) analysis, along with the Detrended Fluctuation Analysis (DFA), for self-affinity studies of the evolving dynamical datasets.

Results: We notably observe a significant asymmetry of distributions shows from skewness and the presence of heavy tails is noted from kurtosis. The daily infection and death data are, by and large, nonstationary, while their corresponding log return values render stationarity. The self-affinity studies through the Hurst exponents and DFA exhibit intriguing local changes over time. These changes can be attributed to the underlying dynamics of state transitions, especially from a random state to either mean-reversion or long-range memory/persistence states.

Conclusions: We conduct systematic studies covering a widely diverse time series datasets of the daily infections and deaths during the evolution of the COVID-19 pandemic. We demonstrate the merit of a multiple analytics frameworks through systematically laying down a methodological structure for analyses and quantitatively examining the evolution of the daily COVID-19 infection and death cases. This methodology builds a capability for tracking dynamically evolving states pertaining to critical problems.

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采用数据驱动方法研究六大洲12个国家COVID-19感染和死亡时间序列的时间特征。
背景:本研究采用数据驱动的方法,综合多种分析方法,研究COVID-19日感染和死亡时间序列特征,并确定可证实该疾病时间演变的相关性和特征趋势。这些数据集涵盖了2020年1月22日至2022年3月1日期间六大洲的12个不同国家。这段时间被划分为三个窗口:(1)疫苗前,(2)疫苗后和组粒前(BA.1变异),以及(3)疫苗后包括组粒后变异。这项研究使我们能够深入了解与COVID-19进化相关的系统动力学科学的有趣问题。方法:我们实施了一套不同的分析方法:(a)统计研究,以估计数据分布的偏度和峰度;(b)利用增广Dickey-Fuller (ADF)检验分析这些时间序列的平稳性;(c)使用philips - ouliaris (PO)检验非平稳时间序列的协整特性;(d)利用重新标度范围(R/S)分析和去趋势波动分析(DFA)计算Hurst指数,用于不断发展的动态数据集的自亲和性研究。结果:我们明显地观察到分布的不对称性,从偏度和峰度中可以看出重尾的存在。总的来说,每日感染和死亡数据是非平稳的,而它们对应的对数返回值呈现平稳。通过赫斯特指数和DFA进行的自亲和研究显示出有趣的局部变化。这些变化可以归因于状态转换的潜在动态,特别是从随机状态到均值回归或长期记忆/持久状态。结论:我们进行了系统研究,涵盖了COVID-19大流行演变过程中日常感染和死亡的广泛不同时间序列数据集。我们通过系统地制定用于分析和定量检查每日COVID-19感染和死亡病例演变的方法结构,展示了多种分析框架的优点。该方法建立了跟踪与关键问题相关的动态发展状态的能力。
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来源期刊
BMC Medical Research Methodology
BMC Medical Research Methodology 医学-卫生保健
CiteScore
6.50
自引率
2.50%
发文量
298
审稿时长
3-8 weeks
期刊介绍: BMC Medical Research Methodology is an open access journal publishing original peer-reviewed research articles in methodological approaches to healthcare research. Articles on the methodology of epidemiological research, clinical trials and meta-analysis/systematic review are particularly encouraged, as are empirical studies of the associations between choice of methodology and study outcomes. BMC Medical Research Methodology does not aim to publish articles describing scientific methods or techniques: these should be directed to the BMC journal covering the relevant biomedical subject area.
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