Axial Spondyloarthritis Clinical Research Year in Review: SPARTAN 2024 Annual Meeting Proceedings.

IF 5.7 2区医学 Q1 RHEUMATOLOGY Current Rheumatology Reports Pub Date : 2025-01-04 DOI:10.1007/s11926-024-01178-1

Mohamad Bittar

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Abstract

Purpose of review: The purpose of this review is to highlight high impact clinical research in axial spondyloarthritis that was published between May 2023 and April 2024. These publications were presented at the SPARTAN annual meeting in May 2024.

Recent findings: Three publications addressed the rate and predictors of radiographic progression in axial spondyloarthritis. MRI-based synthetic CT was introduced as a new modality to assess spinal structural damage. One of the first definitions of difficult to treat axial spondyloarthritis was published. Biologic taper, flare rates, and predictors of flares were discussed. Minimally invasive one-level osteotomy can be an option to correct kyphosis with less risk compared to standard approach. Different therapeutic classes seem to be protective against anterior uveitis in axial spondyloarthritis. Patients who receive biologic or targeted synthetic disease modifying antirheumatic drugs are at increased risk of non-serious infections, but not serious infections that are associated with hospitalization or mortality. This year-in-review session covered different concepts, including imaging and radiographic progression, difficult to treat axial spondyloarthritis, biologic taper, surgery, anterior uveitis, and risk of infections.

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中轴性脊柱炎临床研究年度回顾：SPARTAN 2024年年会论文集。

综述目的：本综述的目的是突出2023年5月至2024年4月期间发表的对轴性脊柱炎有高影响的临床研究。这些出版物在2024年5月的斯巴达年会上发表。最近的发现：三篇出版物讨论了轴性脊柱炎的放射学进展率和预测因素。基于mri的合成CT作为评估脊柱结构损伤的新方法被引入。第一个难以治疗的轴性脊柱性关节炎的定义发表。讨论了生物锥度、耀斑率和耀斑预测因子。与标准入路相比，微创单节段截骨术是一种风险较小的矫正后凸的方法。不同的治疗类别似乎对轴性脊柱炎的前葡萄膜炎有保护作用。接受生物或靶向合成抗风湿药物治疗的患者发生非严重感染的风险增加，但发生与住院或死亡相关的严重感染的风险没有增加。这一年的回顾会议涵盖了不同的概念，包括影像学和影像学进展、难以治疗的轴型脊柱炎、生物锥、手术、前葡萄膜炎和感染风险。

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来源期刊

Current Rheumatology Reports RHEUMATOLOGY-

CiteScore

11.20

自引率

0.00%

发文量

期刊介绍： This journal aims to review the most important, recently published research in the field of rheumatology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of rheumatologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as the many forms of arthritis, osteoporosis and metabolic bone disease, and systemic lupus erythematosus. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.