Maíra Casalechi, Maria Thereza V Pereira, Wiviane A Assis, Cynthia Dela Cruz, Tays F Guedes, Ines Katerina Cavallo, Fernando M Reis
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引用次数: 0
Abstract
This study investigated whether luteinizing hormone receptor (LHR) expression varies in the granulosa cells of individual follicles according to the maturation stage of the oocytes harvested for assisted reproductive technology treatment. We observed minimal to no LHR messenger ribonucleic acid and protein expression in cumulus cells surrounding oocytes arrested in the germinal vesicle stage. Interestingly, their ability to mature was confirmed by rescue in vitro maturation, suggesting somatic cell LHR deficiency as a key factor for the retrieval of germinal vesicle oocytes in assisted reproductive technology procedures.
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