Gestational diabetes and other maternal and neonatal-associated conditions could improve after bariatric surgery.

Micaela Milagros Rossi, Franco José Signorini, Ramiro Leandro Veliz, Martín Andrada, Nicolás Zoela, Sofía Ramirez, Federico Moser
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Abstract

Background: Women represent 40% of patients undergoing bariatric surgery. This highlights the importance of understanding its effects on pregnancy and newborns (NBs).

Objective: To compare pregnancy and neonatal outcomes between a group of pregnant women with obesity and those who had prior bariatric surgery.

Setting: University Hospital, Argentina; Private Practice.

Methods: A retrospective analysis of patients with bariatric surgery before pregnancy (n = 49) and women with obesity (body mass index [BMI] ≥ 30 kg/m2) without previous bariatric surgery (n = 146) was performed. Variables assessed included type of bariatric surgery, age at pregnancy, interval between surgery and conception, maternal weight and BMI at pregnancy onset and end, weight gain during pregnancy, NB weight, gestational age, premature birth, macrosomia, low birth weight, pregnancy-induced hypertension, gestational diabetes mellitus (GDM), anemia, pre-eclampsia, congenital anomalies, fetal deaths, and mode of delivery.

Results: BMI at the start and end of pregnancy was lower in the postbariatric group compared to the group with obesity (P < .001). Weight gain during pregnancy was greater in the postbariatric group compared to the group with obesity (P < .001). The weight of NBs was lower in the postbariatric group compared to the group with obesity (P < .001). The incidence of GDM was lower in the postbariatric group compared to the group with obesity (P < .001). Other variables did not show significant differences between the 2 groups.

Conclusion: Pregnant women with obesity have high rates of gestational diabetes and neonatal macrosomia compared to those who underwent surgery.

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妊娠期糖尿病和其他母婴相关疾病在减肥手术后可能得到改善。
背景:女性占接受减肥手术患者的40%。这突出了了解其对妊娠和新生儿(NBs)影响的重要性。目的:比较一组肥胖孕妇和之前做过减肥手术的孕妇的妊娠和新生儿结局。地点:阿根廷大学医院;私人执业。方法:回顾性分析怀孕前接受过减肥手术的患者(n = 49)和未接受过减肥手术的肥胖(体重指数[BMI]≥30 kg/m2)女性(n = 146)。评估的变量包括减肥手术类型、妊娠年龄、手术和受孕间隔、妊娠开始和结束时母亲体重和BMI、妊娠期间体重增加、新生儿体重、胎龄、早产、巨大儿、低出生体重、妊娠性高血压、妊娠期糖尿病(GDM)、贫血、先兆子痫、先天性异常、胎儿死亡和分娩方式。结果:与肥胖组相比,减肥后组妊娠开始和结束时的BMI均较低(P < 0.001)。与肥胖组相比,减肥后组怀孕期间体重增加更大(P < 0.001)。与肥胖组相比,减肥后组NBs体重较低(P < 0.001)。与肥胖组相比,减肥后组的GDM发病率较低(P < 0.001)。其他变量在两组间无显著差异。结论:与接受手术的孕妇相比,肥胖孕妇妊娠期糖尿病和新生儿巨大儿的发生率较高。
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