Ye Li, Dong-Wei Wang, Jian-Quan Liu, Xiang-Shan Wang
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引用次数: 0
Abstract
Herein, we present a Pd(OAc)2/Dppp-catalyzed synthesis of 4-arylphenanthridinones from 2-bromobenzamides and iodobenzene, which undergoes successive Ullman cross-coupling, C–H activation, and oxidative coupling dehydrogenation process. The presented methods offer an adaptable and modular synthesis route for efficiently producing a wide array of valuable phenanthridiones, demonstrating exceptional compatibility with functional groups. Alternatively, a 1:1 cross-coupling reaction utilizing an intramolecular norbornene moiety as the ligand resulted in phenanthridinones through N-arylation and C–H activation.
期刊介绍：
Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.
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