Digital cognitive training for functionality in mild cognitive impairment: a randomized controlled clinical trial

IF 5.4 2区 医学 Q1 GERIATRICS & GERONTOLOGY GeroScience Pub Date : 2025-01-06 DOI:10.1007/s11357-024-01464-x
Cíntia Monteiro Carvalho, Bruno Costa Poltronieri, Karin Reuwsaat, Maria Eduarda Alves Reis, Rogerio Panizzutti
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Abstract

Digital cognitive training may improve cognition in people with mild cognitive impairment (MCI); however, the effect on functionality remains poorly defined. The Canadian Occupational Performance Measure (COPM) is a valid and consistent instrument for evaluating the performance of activities of daily living in this population. This study used the COPM to investigate the effects of digital cognitive training on functionality in individuals with MCI. We recruited participants aged 60 or older with MCI to a double-blinded, randomized, stepped wedge clinical trial of digital cognitive training compared to an active control group of commercial computer games. Participants were evaluated for functionality and cognition before and after 10 h of intervention. Ten hours of digital cognitive training improved functionality, measured by COPM performance, compared to the active control group. Learning over trials also improved significantly after 10 h of digital cognitive training, as compared to the active control group. Ten hours of digital cognitive training improved functionality in MCI. More sensitive tools, such as COPM, should be used to evaluate the effect of therapeutic interventions for functionality in MCI.

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轻度认知障碍患者的数字认知功能训练:一项随机对照临床试验
数字认知训练可能改善轻度认知障碍(MCI)患者的认知;然而,对功能的影响仍然不明确。加拿大职业表现衡量(COPM)是评估这一人群日常生活活动表现的有效和一致的工具。本研究使用COPM来调查数字认知训练对MCI患者功能的影响。我们招募了60岁或60岁以上的MCI患者进行双盲、随机、阶梯形临床试验,将数字认知训练与商业电脑游戏的积极对照组进行比较。在干预前后10小时评估参与者的功能和认知。与积极的对照组相比,10小时的数字认知训练提高了功能,通过COPM表现来衡量。与积极的对照组相比,经过10小时的数字认知训练后,试验中的学习能力也有了显著提高。10小时的数字认知训练改善了轻度认知障碍的功能。更敏感的工具,如COPM,应用于评估治疗干预对MCI功能的影响。
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来源期刊
GeroScience
GeroScience Medicine-Complementary and Alternative Medicine
CiteScore
10.50
自引率
5.40%
发文量
182
期刊介绍: GeroScience is a bi-monthly, international, peer-reviewed journal that publishes articles related to research in the biology of aging and research on biomedical applications that impact aging. The scope of articles to be considered include evolutionary biology, biophysics, genetics, genomics, proteomics, molecular biology, cell biology, biochemistry, endocrinology, immunology, physiology, pharmacology, neuroscience, and psychology.
期刊最新文献
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