Finite Element Model of Patient-Specific Flanged Acetabular Components Highlights Biomechanical Effects of Bone Density and Cortical Shell Thickness.

IF 2.1 3区 医学 Q2 ORTHOPEDICS Journal of Orthopaedic Research® Pub Date : 2025-01-05 DOI:10.1002/jor.26037
Haena-Young Lee, Friedrich Boettner, Jason L Blevins, Jose A Rodriguez, Joseph D Lipman, Fernando J Quevedo González, Mathias P Bostrom, Timothy M Wright, Peter K Sculco
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Abstract

Patient-specific flanged acetabular components are utilized to treat failed total hip arthroplasties with severe acetabular defects. We previously developed and published a finite element model that investigated the impact of hip joint center lateralization on construct biomechanics during gait conditions. This model consisted of a patient-specific implant designed to address a superior-medial defect created in a standard pelvic geometry. This study aims to utilize the same model and examine how cortical shell thickness and ischial cancellous bone density affect the strain distribution in the bone and bone-implant micromotion. Using published studies and bone density analyses of patients who had undergone total hip arthroplasties with flanged acetabular components, we established a thickness range for the cortical shell (1.5, 1, and 0.75 mm) and two levels of ischial cancellous bone density (100% and 25%). We compared the resulting bone strains against the fatigue strength of the bone (0.3% strain) as a criterion for local bone failure and the bone-implant micromotion against the threshold associated with bone ingrowth (20 µm). A thinner pelvic cortical shell and lower ischial cancellous bone density increased areas of bone at risk of failure, particularly at the ischial screws (from 6% to 38%), and decreased areas compatible with bone ingrowth. These findings agree with our clinical knowledge that compromised ischial bone and inadequate ischial fixation negatively impact the survivorship of flanged acetabular components. This series establishes our modeling approach of a computational model that can be utilized to guide implant design to best treat unique acetabular defects.

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患者特有的法兰髋臼部件的有限元模型强调骨密度和皮质壳厚度的生物力学效应。
患者特有的髋臼法兰假体用于治疗髋臼严重缺损的全髋关节置换术失败。我们之前开发并发表了一个有限元模型,研究了在步态条件下髋关节中心偏侧对构建生物力学的影响。该模型由患者特异性植入物组成,旨在解决在标准骨盆几何形状中产生的上内侧缺陷。本研究旨在利用相同的模型,研究皮质壳厚度和坐骨松质骨密度如何影响骨应变分布和骨种植体微动。利用已发表的研究和髋臼缘缘全髋关节置换术患者的骨密度分析,我们建立了皮质壳的厚度范围(1.5、1和0.75 mm)和坐骨松质骨密度的两个水平(100%和25%)。我们将得到的骨应变与骨的疲劳强度(0.3%应变)进行比较,作为局部骨衰竭的标准,并将骨种植体微运动与骨长入相关的阈值(20µm)进行比较。较薄的骨盆皮质壳和较低的坐骨松质骨密度增加了骨衰竭的风险区域,特别是坐骨螺钉(从6%增加到38%),并且减少了与骨向内生长相适应的区域。这些发现与我们的临床知识一致,坐骨骨受损和坐骨固定不充分会对法兰髋臼部件的存活产生负面影响。该系列建立了我们的计算模型建模方法,可用于指导植入物设计,以最佳地治疗独特的髋臼缺陷。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Orthopaedic Research®
Journal of Orthopaedic Research® 医学-整形外科
CiteScore
6.10
自引率
3.60%
发文量
261
审稿时长
3-6 weeks
期刊介绍: The Journal of Orthopaedic Research is the forum for the rapid publication of high quality reports of new information on the full spectrum of orthopaedic research, including life sciences, engineering, translational, and clinical studies.
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