Potential of Nature-Derived Biopolymers for Oral Applications- A Review.

IF 3.3 3区 医学 Q2 CHEMISTRY, MEDICINAL Mini reviews in medicinal chemistry Pub Date : 2025-01-02 DOI:10.2174/0113895575359305241218113847
Vijayalakshmi Kumar, Ashok K Sundramoorthy
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Abstract

In recent years, there has been a growing emphasis on the "back-to-nature" movement, which has brought biopolymers derived from natural sources into the spotlight. These biopolymers are gaining attention for their versatile surface-active properties, anti-adhesive capabilities, excellent biocompatibility, non-toxicity, biodegradability, and antimicrobial effectiveness against a wide range of oral microorganisms, including both bacteria and fungi. Researchers have been actively modifying these eco-friendly, nature-based biopolymers to enhance their interaction with surrounding cells and tissues, improving their performance in vivo. This has led to innovative applications in areas such as surface coatings, controlled drug delivery, tissue repair, and dental implant devices. These advancements hold the potential to pave the way for the development of novel drug delivery systems with enhanced therapeutic properties, ultimately supporting the creation of innovative formulations for clinical use. This review aims to provide an up-to-date overview of recent developments, explore potential future directions, and highlight the promising applications of nature-derived biopolymers in oral healthcare.

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天然衍生生物聚合物的口服应用潜力综述。
近年来,人们越来越重视 "回归自然 "运动,这使得从天然来源提取的生物聚合物成为人们关注的焦点。这些生物聚合物具有多种表面活性特性、抗粘附能力、良好的生物相容性、无毒性、生物可降解性以及对多种口腔微生物(包括细菌和真菌)的抗菌效果,因而越来越受到关注。研究人员一直在积极改造这些生态友好、基于自然的生物聚合物,以增强它们与周围细胞和组织的相互作用,从而提高它们在体内的性能。这使得生物聚合物在表面涂层、可控给药、组织修复和牙科植入设备等领域得到了创新性应用。这些进步有可能为开发具有更强治疗特性的新型给药系统铺平道路,最终支持创新配方的临床应用。本综述旨在提供最新的发展概况,探索潜在的未来发展方向,并重点介绍源自大自然的生物聚合物在口腔医疗保健领域的应用前景。
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来源期刊
CiteScore
7.80
自引率
0.00%
发文量
231
审稿时长
6 months
期刊介绍: The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines. Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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