Erica Neill, Ravi Iyer, Philip Sumner, Andrew Mackinnon
{"title":"Time to report estimands in randomised controlled trials","authors":"Erica Neill, Ravi Iyer, Philip Sumner, Andrew Mackinnon","doi":"10.1016/s2215-0366(24)00439-5","DOIUrl":null,"url":null,"abstract":"The first quarter of the 21st century has seen critical advances in the conduct and reporting of clinical trials in all fields of medicine. Beyond the foundational requirement for prospective registration, the widespread adoption of the intention-to-treat principle, appropriate treatment of missing data, and a focus on the clinical relevance of outcomes have predominated. However, there is growing awareness of the need for further refinements in many aspects of our trials.","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"1 1","pages":""},"PeriodicalIF":30.8000,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lancet Psychiatry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/s2215-0366(24)00439-5","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
The first quarter of the 21st century has seen critical advances in the conduct and reporting of clinical trials in all fields of medicine. Beyond the foundational requirement for prospective registration, the widespread adoption of the intention-to-treat principle, appropriate treatment of missing data, and a focus on the clinical relevance of outcomes have predominated. However, there is growing awareness of the need for further refinements in many aspects of our trials.
期刊介绍：
The Lancet Psychiatry is a globally renowned and trusted resource for groundbreaking research in the field of psychiatry. We specialize in publishing original studies that contribute to transforming and shedding light on important aspects of psychiatric practice. Our comprehensive coverage extends to diverse topics including psychopharmacology, psychotherapy, and psychosocial approaches that address psychiatric disorders throughout the lifespan. We aim to channel innovative treatments and examine the biological research that forms the foundation of such advancements. Our journal also explores novel service delivery methods and promotes fresh perspectives on mental illness, emphasizing the significant contributions of social psychiatry.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
