Late-Stage Diazoester Installation via Arylthianthrenium Salts

IF 16.9 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Angewandte Chemie International Edition Pub Date : 2025-01-07 DOI:10.1002/anie.202419931
Dr. Le Li, Sven Müller, Roland Petzold, Prof. Dr. Tobias Ritter
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Abstract

By leveraging the fast oxidative addition of arylthianthrenium salts (aryl-TT+) to palladium(0), a regioselective diazoester installation has been developed. This approach enables the introduction of a diazo moiety to densely functionalized arenes at a late stage. The installed diazo group is amenable to facile further derivatization.

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通过芳硫钍盐进行后期重氮酯安装
通过利用芳基噻吩盐(芳基tt +)对钯(0)的快速氧化加成,开发了一种区域选择性重氮酯装置。这种方法可以在后期将重氮部分引入到密集功能化的芳烃中。所安装的重氮基团易于进一步衍生化。
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来源期刊
CiteScore
26.60
自引率
6.60%
发文量
3549
审稿时长
1.5 months
期刊介绍: Angewandte Chemie, a journal of the German Chemical Society (GDCh), maintains a leading position among scholarly journals in general chemistry with an impressive Impact Factor of 16.6 (2022 Journal Citation Reports, Clarivate, 2023). Published weekly in a reader-friendly format, it features new articles almost every day. Established in 1887, Angewandte Chemie is a prominent chemistry journal, offering a dynamic blend of Review-type articles, Highlights, Communications, and Research Articles on a weekly basis, making it unique in the field.
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