Economics of Dementia Prevention: Why the 2023 World Health Global Guidelines on Dementia May Not Reduce the Dementia Epidemiology in Developing Countries

IF 13 1区 医学 Q1 CLINICAL NEUROLOGY Alzheimer's & Dementia Pub Date : 2025-01-09 DOI:10.1002/alz.094651
Cyprian M Mostert
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Abstract

Background

In 2023, the World Health Organization (WHO) presented the Mental Health Gap Action Programmes to avert Dementia. In this publication, the WHO presented a high certainty that physical activity interventions prevent Dementia. The organization presented low levels of certainty that psychosocial interventions, non-pharmaceutical interventions, depression, and anxiety treatments are effective for Dementia prevention in low-income and middle-income countries (LMICs). This policy paper utilizes Global evidence, Continental perspective, Regional insight, and County outlook and presents the potential global policies that can avert Dementia, which were omitted in the 2023 WHO report.

Method

This review uses World Bank, World Health Organization, and United Nations datasets. We also comprehensively searched the medical literature for published articles on social and commercial determinants of Dementia.

Result

We demonstrate that the current WHO report does not comprehensively present policies that may yield positive returns in averting Dementia for developing countries. Physical activity is high in LMICs and may do little to prevent Dementia. Countries need to reduce poverty, hunger, tobacco consumption, alcohol consumption, sugar consumption, and other substances as crucial risk factors that drive Dementia outcomes in LMICs. Other policies that may improve Dementia epidemiology are welfare programs presented in Figure 1. These policies have robust chance of averting sixty percent of the Dementia cases.

Conclusion

There is a significant risk of failing to improve Dementia outcomes if the current 2023 WHO report is not amended. Policymakers must address both the social and commercial determinants factors of Dementia as countries seek to achieve healthy brain aging.

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痴呆症预防经济学:为什么2023年世界卫生痴呆症全球指南可能不会减少发展中国家的痴呆症流行病学
2023年,世界卫生组织(世卫组织)提出了预防痴呆症的精神卫生差距行动规划。在这份出版物中,世卫组织提出了一个高度肯定的观点,即体育活动干预可以预防痴呆症。该组织表示,在低收入和中等收入国家(LMICs),社会心理干预、非药物干预、抑郁和焦虑治疗对预防痴呆症有效的确定性较低。本政策文件利用全球证据、大陆视角、区域洞察力和国家前景,提出了可以预防痴呆症的潜在全球政策,这些政策在2023年世卫组织报告中被遗漏。方法本综述使用世界银行、世界卫生组织和联合国的数据集。我们还全面检索了关于痴呆症的社会和商业决定因素的医学文献。结果我们证明,目前的世卫组织报告没有全面提出可能在发展中国家预防痴呆症方面产生积极回报的政策。中低收入国家的体育活动较多,但对预防痴呆症的作用可能不大。各国需要减少贫困、饥饿、烟草消费、酒精消费、糖消费和其他物质,这些物质是导致中低收入国家痴呆症结局的关键风险因素。其他可能改善痴呆症流行病学的政策是如图1所示的福利计划。这些政策有很大的机会避免60%的痴呆症病例。结论:如果不修改目前的世卫组织2023年报告,将存在无法改善痴呆症预后的重大风险。在各国寻求实现大脑健康老龄化的过程中,决策者必须解决痴呆症的社会和商业决定因素。
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来源期刊
Alzheimer's & Dementia
Alzheimer's & Dementia 医学-临床神经学
CiteScore
14.50
自引率
5.00%
发文量
299
审稿时长
3 months
期刊介绍: Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.
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