Rufus O. Akinyemi, Oludotun V Olalusi, Tolulope O Akinyemi, Joseph O Yaria, Gabriel O Ogunde, Joshua O. Akinyemi, Brian Lawlor, Adesola Ogunniyi
{"title":"Determinants of hand grip strength among community dwelling older adults in southwestern Nigeria: Data from the VALIANT Study","authors":"Rufus O. Akinyemi, Oludotun V Olalusi, Tolulope O Akinyemi, Joseph O Yaria, Gabriel O Ogunde, Joshua O. Akinyemi, Brian Lawlor, Adesola Ogunniyi","doi":"10.1002/alz.093554","DOIUrl":null,"url":null,"abstract":"BackgroundHand‐grip strength (HGS) is known to be a surrogate marker of not only fitness and frailty, but of cognitive and cardiometabolic health. It is cheap, readily deployed and can be a valuable tool in resource‐limited settings. Little however is known about the determinants and correlates of HGS in sub‐Saharan Africa, where stroke and vascular cognitive disorders are projected to exponentially increase. We examined the determinants of HGS among older adults in a rural community in Ibadan, South West Nigeria.MethodVascular heAlth, fraiLty and cognition in Ageing Nigerians (VALIANT) Study is an ongoing longitudinal community‐based cohort study aimed at exploring the association between cardiovascular health, cognition and frailty in Nigeria. One thousand (1000) participants have so far been recruited (via a multistage, stratified cluster random sampling method) and have been taken through a battery of cardiovascular, cognitive and frailty assessment tools. Data on HGS, obtained using a digital hand dynamometer, was available for 480 men and women aged ≥50years. A multivariable adjusted linear regression analysis was used to assess the determinants of HGS. All associations were reported as coefficients with 95% confidence intervals (CI)ResultThe mean age was 64.5 (11.8) with 35% males. The mean HGS was higher among males (22.86 10.1) than in females (16.26 6.1) (p<0.001) and decreased with increasing age and in the left hand. Using the Rockwood frailty scale, 66 (13.8%) of the study participants were vulnerable to frail while 80% had cognitive impairment (MoCA <26). In the multivariable linear regression analysis, the independent determinants of hand grip strength with corresponding beta coefficients (95%CI) were attainment of tertiary/postgraduate education 5.19 (1.70; 8.68), being a widow/widower ‐2.75 (‐5.47; ‐0.03), lower MoCA score<19 ‐2.50 (‐4.42; ‐0.59) and higher IDEA‐IADL score 0.23 (0.02, 0.44)ConclusionAmongst older adults in rural Nigeria, attainment of tertiary/postgraduate education was independently associated with higher HGS; while being a widow/widower and presence of low cognitive reserve were independently associated with lower HGS. This study has identified unique determinants of HGS among West Africans.","PeriodicalId":7471,"journal":{"name":"Alzheimer's & Dementia","volume":"14 1","pages":""},"PeriodicalIF":13.0000,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alzheimer's & Dementia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/alz.093554","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
BackgroundHand‐grip strength (HGS) is known to be a surrogate marker of not only fitness and frailty, but of cognitive and cardiometabolic health. It is cheap, readily deployed and can be a valuable tool in resource‐limited settings. Little however is known about the determinants and correlates of HGS in sub‐Saharan Africa, where stroke and vascular cognitive disorders are projected to exponentially increase. We examined the determinants of HGS among older adults in a rural community in Ibadan, South West Nigeria.MethodVascular heAlth, fraiLty and cognition in Ageing Nigerians (VALIANT) Study is an ongoing longitudinal community‐based cohort study aimed at exploring the association between cardiovascular health, cognition and frailty in Nigeria. One thousand (1000) participants have so far been recruited (via a multistage, stratified cluster random sampling method) and have been taken through a battery of cardiovascular, cognitive and frailty assessment tools. Data on HGS, obtained using a digital hand dynamometer, was available for 480 men and women aged ≥50years. A multivariable adjusted linear regression analysis was used to assess the determinants of HGS. All associations were reported as coefficients with 95% confidence intervals (CI)ResultThe mean age was 64.5 (11.8) with 35% males. The mean HGS was higher among males (22.86 10.1) than in females (16.26 6.1) (p<0.001) and decreased with increasing age and in the left hand. Using the Rockwood frailty scale, 66 (13.8%) of the study participants were vulnerable to frail while 80% had cognitive impairment (MoCA <26). In the multivariable linear regression analysis, the independent determinants of hand grip strength with corresponding beta coefficients (95%CI) were attainment of tertiary/postgraduate education 5.19 (1.70; 8.68), being a widow/widower ‐2.75 (‐5.47; ‐0.03), lower MoCA score<19 ‐2.50 (‐4.42; ‐0.59) and higher IDEA‐IADL score 0.23 (0.02, 0.44)ConclusionAmongst older adults in rural Nigeria, attainment of tertiary/postgraduate education was independently associated with higher HGS; while being a widow/widower and presence of low cognitive reserve were independently associated with lower HGS. This study has identified unique determinants of HGS among West Africans.
期刊介绍:
Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.