Scott A Bowler, Thomas A Premeaux, Leo Ratzan, Courtney Friday, Sara Gianella, Alan L Landay, Lishomwa C Ndhlovu
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引用次数: 0
Abstract
A segment of people with HIV on effective antiretroviral therapy (ART) continue to experience poor immune recovery, leaving them at heightened risk of non-AIDS-defining events (NAEs). The production of anti-CD4 IgG autoreactive antibodies is suggested as one contributing mechanism to these complications. Here, we found that plasma anti-CD4 levels do not discriminate immunological responders from nonresponders nor predict the occurrence of NAEs, suggesting it is unlikely a contributing immunopathological factor associated with these complications.
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