Anatomical Aspects and Long-Term Outcomes of Additional Surgical Repair During Heart Transplantation in Adult Congenital Heart Disease.

IF 3.1 3区 医学 Q2 ENGINEERING, BIOMEDICAL ASAIO Journal Pub Date : 2025-01-27 DOI:10.1097/MAT.0000000000002353
Nicola Pradegan, Claudia Cattapan, Chiara Tessari, Giuseppe Toscano, Augusto D'Onofrio, Vincenzo Tarzia, Antonio Gambino, Marny Fedrigo, Vladimiro L Vida, Annalisa Angelini, Gino Gerosa
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Abstract

Adult patients with congenital heart disease (ACHD) requiring heart transplantation (HT) usually show complex anatomies, posing surgical challenges. Consequently, we analyzed technical aspects and early and long-term outcomes of additional surgical repairs during HT in ACHD. Forty patients were identified (23 males, median age: 38 years, interquartile range [IQR]: 26-50). Of these, 17 (42.5%) required additional surgical repair (7 systemic veins repair, 13 pulmonary arteries repair). These procedures were more associated with univentricular physiology ( p < 0.001) and prior Fontan palliation ( p < 0.001). Eight (20.0%) experienced 30 day mortality. At a median follow-up of 5.6 (IQR: 2.0-11.9) years, 5 (12.5%) patients died. Additional surgical repair did not affect postoperative 30 day and long-term follow-up mortality ( p = 0.451 and p = 0.330, respectively).

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成人先天性心脏病心脏移植过程中额外手术修复的解剖学方面和长期结果。
需要心脏移植的成年先天性心脏病(ACHD)患者通常具有复杂的解剖结构,这给手术带来了挑战。因此,我们分析了技术方面以及ACHD HT期间额外手术修复的早期和长期结果。共纳入40例患者,其中男性23例,中位年龄38岁,四分位数间距[IQR]: 26-50。其中17例(42.5%)需要额外的手术修复(7例全身静脉修复,13例肺动脉修复)。这些手术与单室生理学(p < 0.001)和先前的Fontan姑息治疗(p < 0.001)更相关。8例(20.0%)30天死亡。中位随访5.6年(IQR: 2.0-11.9), 5例(12.5%)患者死亡。额外手术修复不影响术后30天死亡率和长期随访死亡率(p = 0.451和p = 0.330)。
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来源期刊
ASAIO Journal
ASAIO Journal 医学-工程:生物医学
CiteScore
6.60
自引率
7.10%
发文量
651
审稿时长
4-8 weeks
期刊介绍: ASAIO Journal is in the forefront of artificial organ research and development. On the cutting edge of innovative technology, it features peer-reviewed articles of the highest quality that describe research, development, the most recent advances in the design of artificial organ devices and findings from initial testing. Bimonthly, the ASAIO Journal features state-of-the-art investigations, laboratory and clinical trials, and discussions and opinions from experts around the world. The official publication of the American Society for Artificial Internal Organs.
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