Increasing Incidence of Facial Nerve Disorders in the United States from 2007 to 2022

IF 2 3区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Laryngoscope Pub Date : 2025-01-10 DOI:10.1002/lary.31997

Eric X. Wei MD, Allen Green BS, Jon-Paul Pepper MD, Sarah R. Akkina MD

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Abstract

Background

Incidence data on Facial Nerve Disorders (FND) and Bell's palsy are currently limited. Prior epidemiological studies have estimated the incidence rate of Bell's palsy to be between 11 and 53/100,000 individuals, although the most cited incidence data are from single regions or municipalities, many of which are outdated from several decades ago.

Methods

This was a retrospective cohort study of US adults from 2007 to 2022 using the Merative™ Marketscan® Research Databases. Trends in the incidence of FND were described overall and by specific sociodemographic groups, including age, sex, region, and insurance plan type. Chi-squared and simple logistic regression analyses were performed.

Results

From 2007 to 2022, the total adult incidence of all FND was 30.5/100,000, and the total incidence of Bell's palsy alone was 24.5/100,000. Over the study period, there was a significant annual increase of 2.1 cases of FND/100,000 adults (95% Confidence Interval [CI] 1.8, 2.3; p < 0.001), and a significant total increase of 1.5 cases of Bell's palsy/100,000 adults (95% CI 1.2, 1.7; p < 0.001). The total incidence of FND was higher in males (33.1/100,000) than in females (28.4/100,000, p < 0.001), and greater in older age groups (p < 0.001). Additionally, the incidence of FND varied significantly by region (p < 0.001) and insurance plan type (p < 0.001).

Conclusions

This study provides up-to-date incidence rates for Bell's palsy and facial nerve disorders, based on national administrative claims data. Incidence rates of FND and Bell's palsy alone have been increasing in the United States from 2007 to 2022.

Level of Evidence

3 Laryngoscope, 135:2008–2013, 2025

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从2007年到2022年，美国面神经疾病的发病率不断增加。

背景：目前面神经疾病（FND）和贝尔氏麻痹的发病率数据有限。先前的流行病学研究估计，贝尔氏麻痹的发病率在每10万人中有11到53人之间，尽管被引用最多的发病率数据来自单个地区或直辖市，其中许多数据是几十年前的过时数据。方法：使用Merative™Marketscan®研究数据库，对2007年至2022年的美国成年人进行回顾性队列研究。FND发病率的趋势被总体描述，并按特定的社会人口群体，包括年龄、性别、地区和保险计划类型。进行卡方和简单逻辑回归分析。结果：2007 - 2022年，所有FND的成人总发病率为30.5/10万，仅贝尔麻痹的总发病率为24.5/10万。在研究期间，每10万成年人中FND病例每年显著增加2.1例(95%置信区间[CI] 1.8, 2.3；结论：基于国家行政索赔数据，本研究提供了贝尔氏麻痹和面神经疾病的最新发病率。在美国，从2007年到2022年，FND和贝尔氏麻痹的发病率一直在上升。证据级别：III喉镜，2025年。

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来源期刊

Laryngoscope 医学-耳鼻喉科学

CiteScore

6.50

自引率

7.70%

发文量

500

审稿时长

2-4 weeks

期刊介绍： The Laryngoscope has been the leading source of information on advances in the diagnosis and treatment of head and neck disorders since 1890. The Laryngoscope is the first choice among otolaryngologists for publication of their important findings and techniques. Each monthly issue of The Laryngoscope features peer-reviewed medical, clinical, and research contributions in general otolaryngology, allergy/rhinology, otology/neurotology, laryngology/bronchoesophagology, head and neck surgery, sleep medicine, pediatric otolaryngology, facial plastics and reconstructive surgery, oncology, and communicative disorders. Contributions include papers and posters presented at the Annual and Section Meetings of the Triological Society, as well as independent papers, "How I Do It", "Triological Best Practice" articles, and contemporary reviews. Theses authored by the Triological Society’s new Fellows as well as papers presented at meetings of the American Laryngological Association are published in The Laryngoscope. • Broncho-esophagology • Communicative disorders • Head and neck surgery • Plastic and reconstructive facial surgery • Oncology • Speech and hearing defects