Case Report: Utility of brain [18F]FDG PET/CT in the diagnosis of Sydenham's chorea.

Abel Dambrain, Charles Boursot, Kévin Cohen Tannugi, Julien Reichart, Franck Lacoeuille
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Abstract

Sydenham's chorea is an autoimmune reaction against cerebral basal ganglia associated with rheumatic fever, caused by group A beta-hemolytic streptococcus infection. Diagnosis of this condition is difficult because of significant delay between infection onset and symptoms presentation, resulting in few positive biological tests or imaging exams. We report the case of a nine-year-old boy exhibiting hemicorporal abnormal movements with tics for whom [18F]FDG PET/CT exam allowed to make the diagnosis, associated with anti-DNase B elevation. Other biology, spinal tap, EEG and imaging modality like MRI or scanner, were non-contributory.

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病例报告:脑[18F]FDG PET/CT在Sydenham舞蹈病诊断中的应用。
西德纳姆氏舞蹈病是一种与风湿热相关的大脑基底神经节的自身免疫反应,由A群乙型溶血性链球菌感染引起。这种疾病的诊断很困难,因为从感染开始到出现症状之间有明显的延迟,导致很少有阳性的生物检查或影像学检查。我们报告一个9岁男孩的病例,他表现出半躯体异常运动并抽搐,[18F]FDG PET/CT检查允许做出诊断,与抗dna酶B升高有关。其他生物学、脊髓穿刺、脑电图和成像方式(如MRI或扫描仪)都没有贡献。
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Editorial: Nuclear medicine advances through artificial intelligence and intelligent informatics. Case Report: Utility of brain [18F]FDG PET/CT in the diagnosis of Sydenham's chorea. Immunohistochemical basis for FAP as a candidate theranostic target across a broad range of cholangiocarcinoma subtypes. SMART-PET: a Self-SiMilARiTy-aware generative adversarial framework for reconstructing low-count [18F]-FDG-PET brain imaging. Editorial: Recent advances in radiotheranostics.
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