Rapid-recovery protocol for minimally invasive mitral valve repair

Amy Brown MD, MPH , Ali Fatehi Hassanabad MD , Jolene Moen RN , Karen Wiens RN , Alexander J. Gregory MD , Ken Kuljit S. Parhar MD , Corey Adams MD , William D.T. Kent MD
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Abstract

Background

Minimally invasive mitral valve repair (MIMVR), often performed within specialized care pathways, has been shown to reduce hospital length of stay and improve patient recovery. The relative value of rapid-recovery protocols as a component of care pathways, including enhanced recovery programs (ERPs), has not been well described. This study compared clinical outcomes following implementation of a new, comprehensive rapid-recovery protocol within a previously established, mature ERP for patients undergoing MIMVR.

Methods

The rapid-recovery protocol was developed and implemented by a multidisciplinary team to further optimize patient recovery within an existing ERP. The protocol was applied to 75 consecutive patients undergoing MIMVR between September 2022 and December 2023. Outcomes were compared retrospectively to 75 ERP control patients who did not receive the rapid-recovery protocol but experienced the ERP. The primary outcome was a composite of discharge from the intensive care unit (ICU) by postoperative day (POD) 1, discharge to home by POD 4, and no all-cause hospital readmission by 30 days.

Results

Baseline characteristics were similar in the 2 groups. Patients in the rapid-recovery group achieved the primary composite outcome significantly more often compared to the control group (60% vs 40%, respectively). There was no between-group difference in postoperative complications. Multivariable logistic regression showed that age ≤60 years was significantly associated with rapid-recovery protocol success. Clinical barriers to achieving individual components of the primary outcome were described.

Conclusions

A rapid-recovery protocol for MIMVR was associated with early ICU and hospital discharge. These benefits were safely achieved without any increase in hospital readmission, morbidity, or mortality up to 30 days postoperatively.
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微创二尖瓣修复快速恢复方案。
背景:微创二尖瓣修复(MIMVR)通常在专业护理途径下进行,已被证明可以缩短住院时间并改善患者康复。快速恢复方案作为护理途径的一个组成部分的相对价值,包括增强恢复计划(erp),尚未得到很好的描述。本研究比较了在先前建立的成熟ERP中对MIMVR患者实施新的全面快速恢复方案后的临床结果。方法:快速恢复方案由一个多学科团队开发和实施,以进一步优化现有ERP的患者恢复。该方案在2022年9月至2023年12月期间连续应用于75名接受MIMVR的患者。回顾性比较75例ERP对照患者的结果,这些患者没有接受快速恢复方案,但经历了ERP。主要终点为术后第1天(POD)从重症监护病房(ICU)出院,第4天(POD)出院,30天无全因再入院。结果:两组患者的基线特征相似。与对照组相比,快速恢复组患者实现主要综合结局的频率明显更高(分别为60%和40%)。两组术后并发症发生率无明显差异。多变量logistic回归显示,年龄≤60岁与快速恢复方案的成功显著相关。描述了实现主要结果的各个组成部分的临床障碍。结论:快速恢复方案与早期ICU和出院有关。这些益处是安全实现的,术后30天未出现再入院、发病率或死亡率的增加。
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