Global Burden of Otitis Media Attributable to Secondhand Smoke in 204 Countries and Territories from 1990 to 2019: The Analysis of the Global Burden of Disease Study.

Shuhan Liu, Sirui Wang, Xiaofeng Fan, Wei Tang, Yongran Cheng, Yu Sun, Wendi Shi, Lili Dai
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Abstract

Objective: Secondhand smoke (SHS) is a major public health concern. In this study, we evaluated the global burden of otitis media (OM) due to SHS exposure during 1990-2019 and explored the impact of socioeconomic factors on it.

Methods: With reference to the 2019 Global Burden of Disease (GBD) data, we assessed the OM burden linked to SHS during 1990-2019, stratified by gender, GBD region, and country. Join-point regression models analyzed trends in OM burden by calculating the average annual percent change (AAPC). Spearman's correlation examined the relationship between the Socio-demographic Index (SDI), Healthcare Access and Quality (HAQ) index, and SHS-related OM burden.

Results: During 1990-2019, age-standardized disability-adjusted life years (ASDRs) and age-standardized mortality rates (ASMRs) for OM due to SHS declined globally, with AAPCs of -1.45 for ASDR and -7.97 for ASMR. Significant declines in ASMR were noted in low-to-middle SDI regions. Regionally, Eastern Sub-Saharan Africa had the highest OM-related deaths, while South Asia had the highest disability-adjusted life years. OM burden decreased with higher SDI and HAQ.

Conclusion: Despite global declines, significant regional and national disparities remained, which emphasizes the need for targeted interventions.

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1990年至2019年204个国家和地区因二手烟导致的全球中耳炎负担:全球疾病负担研究分析
目的:二手烟(SHS)是一个主要的公共卫生问题。在本研究中,我们评估了1990-2019年间SHS暴露导致的全球中耳炎(OM)负担,并探讨了社会经济因素对其的影响。方法:参考2019年全球疾病负担(GBD)数据,按性别、GBD地区和国家进行分层,评估1990-2019年与SHS相关的OM负担。结合点回归模型通过计算年均百分比变化(AAPC)来分析OM负担的趋势。Spearman相关检验了社会人口统计指数(SDI)、医疗保健可及性和质量(HAQ)指数与shs相关OM负担之间的关系。结果:在1990-2019年期间,全球范围内SHS引起的OM的年龄标准化残疾调整生命年(ASDRs)和年龄标准化死亡率(ASMRs)下降,ASDR的aapc为-1.45,ASMR为-7.97。低至中等SDI地区的ASMR显著下降。从区域来看,撒哈拉以南非洲东部的om相关死亡人数最高,而南亚的残疾调整生命年数最高。随着SDI和HAQ的增加,OM负担降低。结论:尽管全球下降,但显著的区域和国家差异仍然存在,这强调了有针对性干预措施的必要性。
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