Percutaneous irreversible electroporation of renal cell carcinomas in an acquired solitary kidney: A primary study.

IF 1.3 Journal of cancer research and therapeutics Pub Date : 2024-12-01 Epub Date: 2025-01-10 DOI:10.4103/jcrt.jcrt_16_24
Ziyin Wang, Wei Huang, Jingjing Liu, Qin Liu, Qingbing Wang, Zhiyuan Wu, Yu Zhu, Xiaoyi Ding, Zhongmin Wang
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Abstract

Objective: To evaluate the postoperative complications and prognosis of renal cell carcinoma (RCC) in a solitary kidney after irreversible electroporation (IRE).

Materials and methods: A total of 8 patients with 9 RCCs in a solitary kidney treated with computed tomography (CT)-guided IRE from February 2017 to September 2020 were retrospectively analyzed. Follow-up included contrast-enhanced CT or magnetic resonance imaging examinations at 1 day, 1 week, 1 month, 3 months, 6 months, 12 months, and each year after IRE and the evaluation of the incidence of postoperative complications, renal function changes, local tumor recurrence, and metastasis.

Results: Technical success was achieved in all 8 patients treated with IRE. No serious complications were observed. Recurrence or metastasis occurred in two patients. The renal function and hemoglobin values of the 8 patients before treatment and at the last follow-up showed no significant difference.

Conclusion: IRE is a relatively effective, safe, and feasible treatment for RCCs in a solitary kidney, which improved the effective survival and quality of life of these patients.

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获得性孤立肾肾细胞癌的经皮不可逆电穿孔:一项初步研究。
目的:探讨肾细胞癌(RCC)单侧肾不可逆电穿孔(IRE)术后并发症及预后。材料和方法:回顾性分析2017年2月至2020年9月接受CT引导IRE治疗的8例孤立肾rcc患者。随访包括IRE后第1天、第1周、第1个月、第3个月、第6个月、第12个月、每年的CT增强或磁共振成像检查,评估术后并发症、肾功能改变、局部肿瘤复发、转移的发生率。结果:8例经IRE治疗的患者均获得技术上的成功。无严重并发症。2例发生复发或转移。8例患者治疗前与末次随访时肾功能、血红蛋白值无显著差异。结论:IRE是一种相对有效、安全、可行的治疗孤立肾rcc的方法,可提高患者的有效生存期和生活质量。
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