Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) as a cause of new-onset refractory status epilepticus (NORSE): Case report and review of literature

IF 2.9 4区 医学 Q3 IMMUNOLOGY Journal of neuroimmunology Pub Date : 2025-01-08 DOI:10.1016/j.jneuroim.2025.578522
Abhishek Vaingankar , Ayush Agarwal , Divyani Garg , Pranjal Gupta , Ajay Garg , Divya M. Radhakrishnan , Awadh K. Pandit , Achal Kumar Srivastava
{"title":"Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) as a cause of new-onset refractory status epilepticus (NORSE): Case report and review of literature","authors":"Abhishek Vaingankar ,&nbsp;Ayush Agarwal ,&nbsp;Divyani Garg ,&nbsp;Pranjal Gupta ,&nbsp;Ajay Garg ,&nbsp;Divya M. Radhakrishnan ,&nbsp;Awadh K. Pandit ,&nbsp;Achal Kumar Srivastava","doi":"10.1016/j.jneuroim.2025.578522","DOIUrl":null,"url":null,"abstract":"<div><div>Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare cause of NORSE. We describe the case of a young girl who presented with NORSE associated with MOGAD along with a systematic review of all cases of NORSE associated with MOGAD till date. Seizures associated with MOGAD are usually associated with good outcome but can occasionally be catastrophic and non-responsive to conventional therapies. Early initiation of anti-IL6 therapies might help improve outcomes in such patients.</div></div>","PeriodicalId":16671,"journal":{"name":"Journal of neuroimmunology","volume":"399 ","pages":"Article 578522"},"PeriodicalIF":2.9000,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of neuroimmunology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165572825000025","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare cause of NORSE. We describe the case of a young girl who presented with NORSE associated with MOGAD along with a systematic review of all cases of NORSE associated with MOGAD till date. Seizures associated with MOGAD are usually associated with good outcome but can occasionally be catastrophic and non-responsive to conventional therapies. Early initiation of anti-IL6 therapies might help improve outcomes in such patients.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)作为新发难治性癫痫持续状态(NORSE)的原因:病例报告和文献回顾
髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)是一种罕见的NORSE病因。我们描述了一名年轻女孩的病例,她出现了与MOGAD相关的NORSE,并对迄今为止与MOGAD相关的所有NORSE病例进行了系统回顾。与MOGAD相关的癫痫发作通常具有良好的预后,但偶尔也可能是灾难性的,对常规治疗无反应。早期开始抗il - 6治疗可能有助于改善这类患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of neuroimmunology
Journal of neuroimmunology 医学-免疫学
CiteScore
6.10
自引率
3.00%
发文量
154
审稿时长
37 days
期刊介绍: The Journal of Neuroimmunology affords a forum for the publication of works applying immunologic methodology to the furtherance of the neurological sciences. Studies on all branches of the neurosciences, particularly fundamental and applied neurobiology, neurology, neuropathology, neurochemistry, neurovirology, neuroendocrinology, neuromuscular research, neuropharmacology and psychology, which involve either immunologic methodology (e.g. immunocytochemistry) or fundamental immunology (e.g. antibody and lymphocyte assays), are considered for publication.
期刊最新文献
Editorial Board Motor symptoms at onset and manual dexterity predict cognitive impairment in drug-naïve individuals with multiple sclerosis Thin hematoma and hypertrophic pachymeningitis related to otitis media with antineutrophil cytoplasmic antibody-associated vasculitis (OMAAV) along with rheumatoid meningitis: A case report Toxocara canis-originated recombinant C-type lectin improves the disability scores of experimental autoimmune encephalomyelitis in murine in vivo models. Exploring the role of altered oxi-inflammasome activity in the immunobiology of inflammatory neuropathies
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1