James T. Kennedy, Julie K. Wisch, Aylin Dincer, June Roman, Brian A. Gordon, Benjamin Handen, Tammie L. S. Benzinger, Elizabeth Head, Mark Mapstone, Bradley T. Christian, Dana L. Tudorascu, Charles L. Laymon, Sigan L. Hartley, Patrick Lao, Adam M. Brickman, Shahid H. Zaman, Beau M. Ances
{"title":"Decoding brain structure to stage Alzheimer's disease pathology in Down syndrome","authors":"James T. Kennedy, Julie K. Wisch, Aylin Dincer, June Roman, Brian A. Gordon, Benjamin Handen, Tammie L. S. Benzinger, Elizabeth Head, Mark Mapstone, Bradley T. Christian, Dana L. Tudorascu, Charles L. Laymon, Sigan L. Hartley, Patrick Lao, Adam M. Brickman, Shahid H. Zaman, Beau M. Ances","doi":"10.1002/alz.14519","DOIUrl":null,"url":null,"abstract":"Alzheimer's disease (AD) in Down syndrome (DS) is associated with changes in brain structure. It is unknown if thickness and volumetric changes can identify AD stages and if they are similar to other genetic forms of AD.","PeriodicalId":7471,"journal":{"name":"Alzheimer's & Dementia","volume":"36 1","pages":""},"PeriodicalIF":13.0000,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alzheimer's & Dementia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/alz.14519","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Alzheimer's disease (AD) in Down syndrome (DS) is associated with changes in brain structure. It is unknown if thickness and volumetric changes can identify AD stages and if they are similar to other genetic forms of AD.
期刊介绍：
Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
