Min Xiang, Gang-Yong Liu, Hui-Mei Liu, Wen-Yi Zhou, Guang-Wei Wang, Fei Fei, Yun-Qing Jia and Li-Wen Shen
{"title":"The [4+2] annulation of o-acylamino-aryl MBH carbonates with coumarins: facile access to tetrahydrochromeno[4,3-b]quinolin-6-ones†","authors":"Min Xiang, Gang-Yong Liu, Hui-Mei Liu, Wen-Yi Zhou, Guang-Wei Wang, Fei Fei, Yun-Qing Jia and Li-Wen Shen","doi":"10.1039/D4NJ04654D","DOIUrl":null,"url":null,"abstract":"<p >A [4+2] annulation reaction of <em>o</em>-acylamino-aryl MBH carbonates with 3-substituted coumarins has been developed. This method exhibits excellent substrate tolerance and constructs a series of tetrahydrochromeno[4,3-<em>b</em>]quinolin-6-ones with yields up to 95%. The application value of this method has also been demonstrated through a 50-fold scale-up.</p>","PeriodicalId":95,"journal":{"name":"New Journal of Chemistry","volume":" 3","pages":" 683-686"},"PeriodicalIF":2.7000,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"New Journal of Chemistry","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2025/nj/d4nj04654d","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A [4+2] annulation reaction of o-acylamino-aryl MBH carbonates with 3-substituted coumarins has been developed. This method exhibits excellent substrate tolerance and constructs a series of tetrahydrochromeno[4,3-b]quinolin-6-ones with yields up to 95%. The application value of this method has also been demonstrated through a 50-fold scale-up.
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