The Impact of Air Pollution on Acute Angle-Closure Glaucoma in Hefei, China, 2017-2022: A Time-Series Study.

Si-Tian Zhang, Li-Qing Wang, Yan-Cheng Fang, Wen-Bin Shen, Ying-Long Li, Bing Sun, Yong-Rong Li, Xue-Hai Huang, He-Ting Liu, Fen Huang, Yan-Feng Zhou
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Abstract

Objective: The study investigated the effects of air pollutants on the incidence of acute angle-closure glaucoma (AACG) in Hefei, China.

Methods: A combination of generalized additive models and distributed lag nonlinear models was used to explore the relationship between air pollutants and the incidence of AACG.

Results: Exposure-response curves showed that exposure to PM 2.5 , PM 10 , NO 2 , SO 2 , CO, and O 3 were all positively correlated with the onset of AACG. Among them, NO 2 , and CO having higher relative risk values for AACG onset.

Conclusions: This study highlighted the potential risks of these pollutants and expanded the knowledge of the environmental role in AACG incidence, which will encourage local governments to adopt policy measures and guidance to improve public health.

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合肥2017-2022年大气污染对急性闭角型青光眼影响的时间序列研究
摘要:目的:研究合肥地区大气污染物对急性闭角型青光眼(AACG)发病率的影响。方法:采用广义加性模型(GAM)和分布滞后非线性模型(DLNM)相结合的方法,探讨大气污染物与AACG发病的关系。结果:暴露-反应曲线显示pm2.5、pm10、no2、so2、CO、o3暴露均与AACG发病呈正相关。其中NO 2、CO对AACG发病具有较高的相对危险值。结论:本研究突出了这些污染物的潜在风险,扩大了对环境在AACG发病中的作用的认识,将鼓励地方政府采取政策措施和指导,改善公众健康。
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