A new database to guide reference material selection for dietary supplement and nutrition science.

IF 3.8 2区化学 Q1 BIOCHEMICAL RESEARCH METHODS Analytical and Bioanalytical Chemistry Pub Date : 2025-01-15 DOI:10.1007/s00216-024-05664-4

Adam J Kuszak, Sanem Hosbas Coskun, Stephen A Wise

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Abstract

Rigorous research on the health effects of dietary supplements and related nutritional interventions requires thorough chemical characterization of complex matrices for their composition of macro- and micronutrients, botanical phytochemicals, and potential contaminants. Reference materials (RMs) with metrologically traceable values for these specific properties are ideal analytical tools to ensure requisite chemical measurements are reliable. However, identifying and comparing appropriate RMs for studying dietary ingredients and their metabolites is challenging, creating a barrier to reproducible regulatory testing and research. To address this challenge, the Office of Dietary Supplements at the National Institutes of Health coordinated the development of a new publicly available Reference Materials Search Tool ( https://odsrmst.od.nih.gov/ ) database featuring comprehensive data records and search and comparison functionality. The RMST significantly expands research capacities to discover and select fit for purpose reference materials for dietary supplement and related food and natural product chemical analysis.

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一个新的数据库，以指导参考材料的选择膳食补充剂和营养科学。

要严格研究膳食补充剂和相关营养干预措施对健康的影响，就必须对复杂基质中的宏量和微量营养素、植物营养素和潜在污染物进行全面的化学表征。对这些特定属性具有可计量溯源值的标准物质（RM）是理想的分析工具，可确保必要的化学测量结果可靠。然而，确定和比较用于研究膳食成分及其代谢物的适当标样具有挑战性，给可重复的监管测试和研究带来了障碍。为了应对这一挑战，美国国立卫生研究院膳食补充剂办公室协调开发了一个新的公开参考资料搜索工具 ( https://odsrmst.od.nih.gov/ ) 数据库，该数据库具有全面的数据记录以及搜索和比较功能。RMST 大大提高了研究能力，可用于发现和选择适用于膳食补充剂及相关食品和天然产品化学分析的参考材料。

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来源期刊

Analytical and Bioanalytical Chemistry 化学-分析化学

CiteScore

8.00

自引率

4.70%

发文量

638

审稿时长

2.1 months

期刊介绍： Analytical and Bioanalytical Chemistry’s mission is the rapid publication of excellent and high-impact research articles on fundamental and applied topics of analytical and bioanalytical measurement science. Its scope is broad, and ranges from novel measurement platforms and their characterization to multidisciplinary approaches that effectively address important scientific problems. The Editors encourage submissions presenting innovative analytical research in concept, instrumentation, methods, and/or applications, including: mass spectrometry, spectroscopy, and electroanalysis; advanced separations; analytical strategies in “-omics” and imaging, bioanalysis, and sampling; miniaturized devices, medical diagnostics, sensors; analytical characterization of nano- and biomaterials; chemometrics and advanced data analysis.