Waist Circumference Is a Strong Predictor of a Positive Outcome Evaluated One Year After Sleeve Gastrectomy.

IF 2.9 3区医学 Q1 SURGERY Obesity Surgery Pub Date : 2025-02-01 Epub Date: 2025-01-15 DOI:10.1007/s11695-024-07637-z

Marietta Bracha, Alina Jaroch, Jakub Wojtasik

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Abstract

Background: Bariatric surgeries, such as laparoscopic sleeve gastrectomy (LSG), not only result in significant weight loss but also improve the inflammatory state in obese patients. This study aimed to investigate the effects of LSG on weight loss and inflammation status in bariatric patients 1-year post-procedure.

Methods: This prospective cohort study was conducted from September 2022 to May 2024. Fifty obese adults were enrolled for LSG. All patients underwent assessments of body measurements, as well as levels of interleukin-6 (IL-6) and interleukin-10 (IL-10) at baseline, and then at 3 and 12 months post-surgery.

Results: Twelve months post-surgery, body measurements showed a significant reduction, with a median excess weight loss (%EWL) of 56.8%, indicating the clinical success of the bariatric procedure. %EWL showed a strong correlation with waist circumference (R = - 0.738, p < 0.00001). A logistic regression model indicated that a reduction of just 1 cm in initial waist circumference increases the likelihood of a positive outcome in laparoscopic sleeve gastrectomy by 12%. Moreover, a significant increase was observed for IL-10 (p < 0.0001), simultaneously with a significant decrease in IL-6 (p < 0.0001).

Conclusions: This study provides valuable evidence supporting the benefits of laparoscopic sleeve gastrectomy for both weight loss and reducing inflammation. Waist circumference emerged as a strong predictor of metabolic success 1-year post-surgery, while increased IL-10 levels signaled positive immunological changes.

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腰围是袖式胃切除术一年后评估阳性结果的一个强有力的预测因子。

背景：减肥手术，如腹腔镜袖胃切除术（LSG），不仅可以显著减轻体重，还可以改善肥胖患者的炎症状态。本研究旨在探讨LSG对肥胖患者术后1年体重减轻和炎症状态的影响。方法：该前瞻性队列研究于2022年9月至2024年5月进行。50名肥胖成人参加了LSG。所有患者在基线、术后3个月和12个月均接受了身体测量、白细胞介素-6 （IL-6）和白细胞介素-10 （IL-10）水平的评估。结果：手术后12个月，身体测量显示显着减少，中位超重减轻（%EWL）为56.8%，表明减肥手术的临床成功。结论：本研究为腹腔镜下袖式胃切除术在减轻体重和减少炎症方面的益处提供了有价值的证据。腰围是术后1年代谢成功的有力预测指标，而IL-10水平升高则预示着积极的免疫变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obesity Surgery 医学-外科

CiteScore

5.80

自引率

24.10%

发文量

567

审稿时长

3-6 weeks

期刊介绍： Obesity Surgery is the official journal of the International Federation for the Surgery of Obesity and metabolic disorders (IFSO). A journal for bariatric/metabolic surgeons, Obesity Surgery provides an international, interdisciplinary forum for communicating the latest research, surgical and laparoscopic techniques, for treatment of massive obesity and metabolic disorders. Topics covered include original research, clinical reports, current status, guidelines, historical notes, invited commentaries, letters to the editor, medicolegal issues, meeting abstracts, modern surgery/technical innovations, new concepts, reviews, scholarly presentations and opinions. Obesity Surgery benefits surgeons performing obesity/metabolic surgery, general surgeons and surgical residents, endoscopists, anesthetists, support staff, nurses, dietitians, psychiatrists, psychologists, plastic surgeons, internists including endocrinologists and diabetologists, nutritional scientists, and those dealing with eating disorders.